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Yuan Jin
Researcher at Huazhong University of Science and Technology
Publications - 14
Citations - 1445
Yuan Jin is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Hearing loss & Medicine. The author has an hindex of 3, co-authored 8 publications receiving 1028 citations.
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Journal ArticleDOI
Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study.
Lei Pan,Lei Pan,Mi Mu,Pengcheng Yang,Yu Sun,Runsheng Wang,Junhong Yan,Pibao Li,Baoguang Hu,Jing Wang,Chao Hu,Yuan Jin,Xun Niu,Rongyu Ping,Yingzhen Du,Tianzhi Li,Guogang Xu,Qinyong Hu,Lei Tu +18 more
TL;DR: It is found that digestive symptoms are common in patients with COVID-19 and that the index of suspicion may need to be raised earlier in at-risk patients presenting with digestive symptoms, but further large sample studies are needed to confirm these findings.
Journal ArticleDOI
N-Acetylcysteine Combined With Dexamethasone Treatment Improves Sudden Sensorineural Hearing Loss and Attenuates Hair Cell Death Caused by ROS Stress
TL;DR: In this paper, N-acetylcysteine (NAC) combined with dexamethasone can effectively protect hair cells from oxidative stress when they were both at ineffective concentrations alone.
Journal ArticleDOI
Jervell and Lange-Nielsen Syndrome due to a Novel Compound Heterozygous KCNQ1 Mutation in a Chinese Family.
Yue Qiu,Sen Chen,Xia Wu,Wen-Juan Zhang,Wen Xie,Yuan Jin,Le Xie,Kai Xu,Xue Bai,Hui-Min Zhang,Xiao-Zhou Liu,Xiao-Hui Wang,Yu Sun,Weijia Kong +13 more
TL;DR: Using next-generation sequencing (NGS), a compound heterozygosity for two mutations c.1741A>T and c.477+5G>A in KCNQ1 gene is identified as the possible pathogenic cause of JLNS, which suggested a high risk of cardiac events in a deaf child.
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Local Macrophage-Related Immune Response Is Involved in Cochlear Epithelial Damage in Distinct Gjb2-Related Hereditary Deafness Models
Kai Xu,Sen Chen,Le Xie,Yue Qiu,Xue Bai,Xiao-Zhou Liu,Hui-Min Zhang,Xiao-Hui Wang,Yuan Jin,Yu Sun,Weijia Kong +10 more
TL;DR: In this article, two distinct Cx26-null mouse models were established to investigate the types and underlying mechanisms of immune responses in hereditary deafness caused by genetic mutations, and the results indicate that CX3CL1 signaling regulates macrophage recruitment and that enhancement of macocyte antigen-presenting function is associated with cell degeneration.
Journal ArticleDOI
Hearing Screening Combined with Target Gene Panel Testing Increased Etiological Diagnostic Yield in Deaf Children.
TL;DR: Wang et al. as mentioned in this paper found that the most frequent mutant genes were GJB2, SLC26A4, MYO15A, CDH23, and OTOF.