Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study.
Lei Pan,Lei Pan,Mi Mu,Pengcheng Yang,Yu Sun,Runsheng Wang,Junhong Yan,Pibao Li,Baoguang Hu,Jing Wang,Chao Hu,Yuan Jin,Xun Niu,Rongyu Ping,Yingzhen Du,Tianzhi Li,Guogang Xu,Qinyong Hu,Lei Tu +18 more
TLDR
It is found that digestive symptoms are common in patients with COVID-19 and that the index of suspicion may need to be raised earlier in at-risk patients presenting with digestive symptoms, but further large sample studies are needed to confirm these findings.About:
This article is published in The American Journal of Gastroenterology.The article was published on 2020-04-14 and is currently open access. It has received 1397 citations till now. The article focuses on the topics: Vomiting & Abdominal pain.read more
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Extrapulmonary manifestations of COVID-19.
Aakriti Gupta,Aakriti Gupta,Mahesh V. Madhavan,Kartik Sehgal,Kartik Sehgal,Nandini Nair,Shiwani Mahajan,Tejasav S. Sehrawat,Behnood Bikdeli,Behnood Bikdeli,Neha Ahluwalia,John C. Ausiello,Elaine Wan,Daniel E. Freedberg,Ajay J. Kirtane,Sahil A. Parikh,Mathew S. Maurer,Anna S. Nordvig,Domenico Accili,Joan M. Bathon,Sumit Mohan,Kenneth A. Bauer,Kenneth A. Bauer,Martin B. Leon,Harlan M. Krumholz,Nir Uriel,Mandeep R. Mehra,Mitchell S.V. Elkind,Mitchell S.V. Elkind,Gregg W. Stone,Allan Schwartz,David D. Ho,John P. Bilezikian,Donald W. Landry +33 more
TL;DR: The extrapulmonary organ-specific pathophysiology, presentations and management considerations for patients with COVID-19 are reviewed to aid clinicians and scientists in recognizing and monitoring the spectrum of manifestations, and in developing research priorities and therapeutic strategies for all organ systems involved.
Journal ArticleDOI
Mild or Moderate Covid-19.
TL;DR: Covid-19 (the illness caused by SARS-CoV-2) has a range of clinical manifestations, including cough, fever, malaise, myalgias, gastrointestinal symptom...
Journal ArticleDOI
Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation.
Stephen J. Halpin,Stephen J. Halpin,Stephen J. Halpin,Claire McIvor,Gemma Whyatt,Anastasia Adams,Olivia Harvey,Lyndsay McLean,Christopher Walshaw,Steven Kemp,Joanna Corrado,Rajinder Singh,Tamsin Collins,Rory J O’Connor,Rory J O’Connor,Manoj Sivan,Manoj Sivan,Manoj Sivan +17 more
TL;DR: There is currently very limited information on the nature and prevalence of post‐COVID‐19 symptoms after hospital discharge.
Journal ArticleDOI
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes.
Ruochen Zang,Ruochen Zang,Maria Florencia Gomez Castro,Broc T. McCune,Qiru Zeng,Paul W. Rothlauf,Paul W. Rothlauf,Naomi M. Sonnek,Zhuoming Liu,Kevin Brulois,Kevin Brulois,Xin Wang,Harry B. Greenberg,Harry B. Greenberg,Michael S. Diamond,Matthew A. Ciorba,Sean P. J. Whelan,Siyuan Ding +17 more
TL;DR: In this article, the authors reported productive infection of SARS-CoV-2 in ACE2+ mature enterocytes in human small intestinal enteroids, which may contribute to local and systemic illness and overall disease progression.
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Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis.
Ren Mao,Yun Qiu,Jin Shen He,Jin Yu Tan,Xuehua Li,Jie Liang,Jun Shen,Liang Ru Zhu,Yan Chen,Marietta Iacucci,Siew C. Ng,Subrata Ghosh,Min Hu Chen +12 more
TL;DR: Patients in Hubei province, where the initial COVID-19 outbreak occurred, were more likely to present with abnormal liver functions (p<0·0001) compared with those outside of Hubeo and those with non-severe disease.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
Journal ArticleDOI
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
Xiaobo Yang,Yuan Yu,Jiqian Xu,Huaqing Shu,Jia'an Xia,Hong Liu,Hong Liu,Yongran Wu,Lu Zhang,Zhui Yu,Minghao Fang,Ting Yu,Yaxin Wang,Shangwen Pan,Xiaojing Zou,Shiying Yuan,You Shang,You Shang +17 more
TL;DR: The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.
Journal ArticleDOI
Evidence for gastrointestinal infection of SARS-CoV-2
TL;DR: No abstract available Keywords: ACE2; Gastrointestinal Infection; Oral-Fecal Transmission; SARS-CoV-2.
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