Yuan Wang

TL;DR: Findings indicate that laminar and columnar properties of the neocortex are not unique to mammals and may have evolved from cells and circuits found in more ancient vertebrates, which introduces a previously underutilized level of analysis to components involved in higher cognitive functions.

TL;DR: It is proposed that dense arborizations of Ipc axons may be directed to the distal dendritic bottlebrushes of motion detecting tectal ganglion cells (TGCs) and may provide synchronous activation of a group of adjacent bottlebrushed of different TGCs of the same type via their intralaminar processes, and cross channel activation of different types of T GCs within the same column of visual space.

TL;DR: The laminar and columnar pattern of isthmotectal terminals also suggests a means of interacting with multiple tectofugal pathways, including the stratified subpopulations of tectorotundal neurons participating in motion detection.

TL;DR: The optic tectum (superior colliculus in mammals) (OT/SC) has long helped vertebrates to visually identify moving objects and orient toward attractive ones or escape if the objects seem threatening.

TL;DR: Findings support the notion of FMRP differential neuronal regulation and strongly implicate the contribution of fundamental sensory and motor processing at subcortical levels to FXS pathology.