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Yue Lu
Researcher at Jilin University
Publications - 6
Citations - 114
Yue Lu is an academic researcher from Jilin University. The author has contributed to research in topics: Podocyte & Kidney disease. The author has an hindex of 4, co-authored 6 publications receiving 52 citations.
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Elabela, a newly discovered APJ ligand: Similarities and differences with Apelin.
TL;DR: Elabela is a recently identified peptide in the APJ axis that has beneficial effects on body fluid homeostasis, cardiovascular health, and renal insufficiency, as well as potential benefits for metabolism and diabetes.
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Elabela protects against podocyte injury in mice with streptozocin-induced diabetes by associating with the PI3K/Akt/mTOR pathway.
TL;DR: Elabela acts through the phosphoinositide 3-kinase /Akt/mammalian target of rapamycin signaling pathway and decreases podocyte apoptosis, thereby exhibiting a nephroprotective effect against diabetic nephropathy.
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Sulforaphane suppresses obesity-related glomerulopathy-induced damage by enhancing autophagy via Nrf2
TL;DR: Treatment with SFN limited ORG-induced damage by enhancing podocyte autophagy via Nrf2, and reduced body weight, organ-associated fat weight, and urinary albumin/creatinine ratio in both the preventive treatment and disease intervention regimens.
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Mini-Review: GSDME-Mediated Pyroptosis in Diabetic Nephropathy
TL;DR: In this article, the authors introduced pyroptosis, a newly identified type of lytic programmed cell death, is featured in pore formation in the plasma membrane, swelling, and cell rupture with secretion of cellular contents, especially the inflammatory cytokines.
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Serum elabela and apelin levels during different stages of chronic kidney disease.
Xuehong Lu,Shengmao Liu,Rumei Luan,Wenpeng Cui,Yu Chen,Yixian Zhang,Yue Lu,Hong Zhang,Lin Shi,Lining Miao,Feng Xu +10 more
TL;DR: In CKD patients, serum ELA levels decreased with decreasing eGFR, and this finding may provide a new target for the prediction, diagnosis, and staging of CKD.