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Yue Qi
Researcher at Oregon Health & Science University
Publications - 25
Citations - 696
Yue Qi is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Perfusion & Microcirculation. The author has an hindex of 13, co-authored 22 publications receiving 578 citations. Previous affiliations of Yue Qi include Cardiovascular Institute of the South & La Jolla Institute for Allergy and Immunology.
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Journal ArticleDOI
Augmentation of Muscle Blood Flow by Ultrasound Cavitation Is Mediated by ATP and Purinergic Signaling.
J. Todd Belcik,Brian P. Davidson,Aris Xie,Melinda D. Wu,Mrinal Yadava,Yue Qi,Sherry Liang,Chae Ryung Chon,Azzdine Y. Ammi,Joshua J. Field,Joshua J. Field,Joshua J. Field,Leanne Harmann,Leanne Harmann,Leanne Harmann,William M. Chilian,Joel Linden,Jonathan R. Lindner +17 more
TL;DR: Therapeutic ultrasound using microbubble cavitation to increase muscle perfusion relies on shear-dependent increases in ATP, which can act through a diverse portfolio of purinergic signaling pathways that can reverse hindlimb ischemia in mice for >24 hours and increase muscle blood flow in patients with sickle cell disease.
Journal ArticleDOI
Ultrasound-mediated vascular gene transfection by cavitation of endothelial-targeted cationic microbubbles.
Aris Xie,Todd Belcik,Yue Qi,Terry K. Morgan,Shivam A. Champaneri,Sarah Taylor,Brian P. Davidson,Yan Zhao,Alexander L. Klibanov,Michael A. Kuliszewski,Howard Leong-Poi,Azzdine Y. Ammi,Jonathan R. Lindner +12 more
TL;DR: It is concluded that ultrasound-mediated transfection at safe acoustic pressures can be markedly augmented by endothelial juxtaposition, and this technique is a promising approach for site-specific gene therapy.
Journal ArticleDOI
Molecular imaging of activated von Willebrand factor to detect high-risk atherosclerotic phenotype.
Owen J. T. McCarty,Robert B. Conley,Weihui Shentu,Garth W. Tormoen,Daogang Zha,Aris Xie,Yue Qi,Yan Zhao,Chad L. Carr,Todd Belcik,Douglas R. Keene,Philip G. de Groot,Jonathan R. Lindner +12 more
TL;DR: Molecular imaging using GPIbα as a targeting moiety can detect the presence of activated vWF on the vascular endothelium and may provide a means to noninvasively detect an advanced prothrombotic and inflammatory phenotype in atherosclerotic disease.
Journal ArticleDOI
Detection of Antecedent Myocardial Ischemia With Multiselectin Molecular Imaging
TL;DR: Echocardiographic molecular imaging with a human multi-selectin-targeted contrast agent bearing recombinant human PSGL-1 can detect myocardial ischemia hours after resolution and may potentially be used for rapid bedside evaluation of patients with recent chest pain.
Journal ArticleDOI
Molecular imaging of the paracrine proangiogenic effects of progenitor cell therapy in limb ischemia
Jae Choon Ryu,Brian P. Davidson,Aris Xie,Yue Qi,Daogang Zha,J. Todd Belcik,Evan S. Caplan,Juliana Megan Woda,Catherine C. Hedrick,Richard N. Hanna,Nicholas Lehman,Yan Zhao,Anthony E. Ting,Jonathan R. Lindner +13 more
TL;DR: In limb ischemia, MAPCs stimulate the recruitment of proangiogenic monocytes through endothelial activation and enhanced chemotaxis and these responses are sustained beyond the MAPC lifespan, suggesting that paracrine effects promote flow recovery by rebalancing the immune response toward a more regenerative phenotype.