Y
Yuichi Sakano
Researcher at University of Tokyo
Publications - 15
Citations - 319
Yuichi Sakano is an academic researcher from University of Tokyo. The author has contributed to research in topics: Lanosterol synthase & 2,3-Oxidosqualene. The author has an hindex of 9, co-authored 15 publications receiving 296 citations. Previous affiliations of Yuichi Sakano include University of Shizuoka.
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Journal ArticleDOI
Identification and characterization of carbohydrate molecules in mammalian cells recognized by dengue virus type 2.
Chie Aoki,Kazuya I.P.J. Hidari,Saki Itonori,Akihiro Yamada,Naonori Takahashi,Takeshi Kasama,Futoshi Hasebe,Mohammend Alimul Islam,Ken Hatano,Koji Matsuoka,Takao Taki,Chao-Tan Guo,Tadanobu Takahashi,Yuichi Sakano,Takashi Suzuki,Daisei Miyamoto,Mutsumi Sugita,Daiyo Terunuma,Koichi Morita,Yasuo Suzuki +19 more
TL;DR: It is suggested that multivalent nLc4 oligosaccharide could act as a competitive inhibitor against the binding of dengue virus type 2 to the host cells.
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Clarithromycin inhibits progeny virus production from human influenza virus-infected host cells.
Daisei Miyamoto,Sayaka Hasegawa,Nongluk Sriwilaijaroen,Nongluk Sriwilaijaroen,Sangchai Yingsakmongkon,Sangchai Yingsakmongkon,Hiroaki Hiramatsu,Hiroaki Hiramatsu,Tadanobu Takahashi,Kazuya I.P.J. Hidari,Chao-Tan Guo,Chao-Tan Guo,Chao-Tan Guo,Yuichi Sakano,Takashi Suzuki,Yasuo Suzuki,Yasuo Suzuki +16 more
TL;DR: Findings indicate that CAM acts on a middle to late stage of the viral replication cycle resulting in inhibition of progeny virus production from the infected cells.
Journal ArticleDOI
Molecular cloning, expression, and characterization of adenylate isopentenyltransferase from hop (Humulus lupulus L.).
Yuichi Sakano,Yukio Okada,Akiko Matsunaga,Takaharu Suwama,Takafumi Kaneko,Kazutoshi Ito,Hiroshi Noguchi,Ikuro Abe +7 more
TL;DR: Interestingly, steady-state kinetic analyses revealed that the isopentenylation of ADP and ATP were more efficient than that of AMP as previously reported for A. thaliana AtIPT4.
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Inhibition of human lanosterol synthase by the constituents of Colocasia esculenta (taro).
Yuichi Sakano,Motoh Mutsuga,Rie Tanaka,Hiroyuki Suganuma,Takahiro Inakuma,Masatake Toyoda,Yukihiro Goda,Masaaki Shibuya,Yutaka Ebizuka +8 more
TL;DR: Examination of activity variation among eight taro cultivars indicated that "Aichi-wase" and "Yatsugashira" had the most potent activity for hOSC inhibition.
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Synthesis of digalactosyl diacylglycerols and their structure–inhibitory activity on human lanosterol synthase
TL;DR: Digalactosyl and monogalactocyl diacylglycerols (DGDG and MGDG), which were identified as anti-hyperlipemia active components in Colocasia esculenta (Taro), were synthesized and showed the most potent activity.