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Ikuro Abe
Researcher at University of Tokyo
Publications - 340
Citations - 10552
Ikuro Abe is an academic researcher from University of Tokyo. The author has contributed to research in topics: Polyketide & Chemistry. The author has an hindex of 47, co-authored 305 publications receiving 8778 citations. Previous affiliations of Ikuro Abe include Tokyo City University & University of Shizuoka.
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Journal ArticleDOI
Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes
Journal ArticleDOI
An environmental bacterial taxon with a large and distinct metabolic repertoire
Micheal C. Wilson,Tetsushi Mori,Christian Rückert,Agustinus Robert Uria,Maximilian J. Helf,Maximilian J. Helf,Kentaro Takada,Christine Gernert,Ursula A. E. Steffens,Nina Heycke,Susanne Schmitt,Christian Rinke,Eric J. N. Helfrich,Eric J. N. Helfrich,Alexander O. Brachmann,Cristian Gurgui,Toshiyuki Wakimoto,Matthias Kracht,Max Crüsemann,Ute Hentschel,Ikuro Abe,Shigeki Matsunaga,Jörn Kalinowski,Haruko Takeyama,Jörn Piel,Jörn Piel +25 more
TL;DR: Two phylotypes of the candidate genus ‘Entotheonella’ with genomes of greater than 9 megabases and multiple, distinct biosynthetic gene clusters co-inhabit the chemically and microbially rich marine sponge Theonella swinhoei.
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Biosynthesis of fungal meroterpenoids
Yudai Matsuda,Ikuro Abe +1 more
TL;DR: This review summarizes the molecular bases for their biosyntheses, which were recently elucidated with modern techniques, and also discusses the plausible biosynthetic pathways of other related natural products lacking genetic information.
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Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases
Ikuro Abe,Hiroyuki Morita +1 more
TL;DR: This review covers recent advances in structure and function studies on the chalcone synthase (CHS) superfamily of plant type III polyketide synthases (PKSs), which catalyze iterative decarboxylative condensations of malonyl unit with a CoA-linked starter molecule to produce structurally diverse, pharmaceutically important plant secondary metabolites.
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Enzymatic synthesis of cyclic triterpenes
TL;DR: Recent crystallographic and structure-based mutagenesis studies as well as utilization of chemically synthesized active-site probes have begun to reveal intimate structural details of the enzyme-templated cyclization reactions.