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Yujia Guo
Researcher at Shanxi Medical University
Publications - 14
Citations - 382
Yujia Guo is an academic researcher from Shanxi Medical University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 7, co-authored 12 publications receiving 137 citations.
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Journal ArticleDOI
circPARD3 drives malignant progression and chemoresistance of laryngeal squamous cell carcinoma by inhibiting autophagy through the PRKCI-Akt-mTOR pathway
Wei Gao,Guo Huina,Min Niu,Zheng Xiwang,Yuliang Zhang,Xue Xuting,Yunfeng Bo,Guan Xiaoya,Li Zhongxun,Yujia Guo,Long He,Yu Zhang,Li Li,Jimin Cao,Yongyan Wu +14 more
TL;DR: This study reveals that the novel autophagy-suppressive circPARD3 promotes LSCC progression and chemoresistance through the PRKCI-Akt-mTOR pathway, providing new insights into circRNA-mediated autophagic regulation and potential biomarker and target for LSCC treatment.
Journal ArticleDOI
Circular RNA circCORO1C promotes laryngeal squamous cell carcinoma progression by modulating the let-7c-5p/PBX3 axis
Yongyan Wu,Yuliang Zhang,Zheng Xiwang,Dai Fengsheng,Yan Lu,Dai Li,Min Niu,Guo Huina,Li Wenqi,Xue Xuting,Yunfeng Bo,Yujia Guo,Jiangbo Qin,Yixiao Qin,Liu Hongliang,Yu Zhang,Tao Yang,Li Li,Linshi Zhang,Rui Hou,Shuxin Wen,Changming An,Huizheng Li,Xu Wei,Wei Gao +24 more
TL;DR: Mechanistic studies revealed that circCORO1C competitively bound to let-7c-5p and prevented it from decreasing the level of PBX3, which facilitated the malignant progression of LSCC and may serve as a novel target for LSCC therapy.
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Crosstalk between RNA m6A Modification and Non-coding RNA Contributes to Cancer Growth and Progression.
Dai Fengsheng,Yongyan Wu,Yan Lu,Changming An,Zheng Xiwang,Dai Li,Yujia Guo,Linshi Zhang,Huizheng Li,Xu Wei,Wei Gao +10 more
TL;DR: The functional crosstalk between m6A and non-Coding RNAs, particularly microRNA, long non-coding RNA, and circular RNA, is described, and their roles in tumor regulation are illustrated.
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Effect of HPV Infection on the Occurrence and Development of Laryngeal Cancer: A Review.
Dongli Yang,Yong Shi,Yemei Tang,Hongyu Yin,Yujia Guo,Shuxin Wen,Binquan Wang,Changming An,Yongyan Wu,Wei Gao +9 more
TL;DR: Research progress in investigating HPV infection in terms of DNA, mRNA and protein levels in the occurrence and development of laryngeal cancer and routine HPV detection methods is reviewed.
Journal ArticleDOI
Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target?
TL;DR: Fascin actin-bundling protein 1 (FSCN1) as discussed by the authors is a highly conserved actin bundling protein that cross links F-actin microfilaments into tight, parallel bundles and is recognized as a candidate biomarker for multiple cancer types and as a potential therapeutic target.