Y
Yukari Okamoto
Researcher at Vaccine Research Center
Publications - 1
Citations - 1283
Yukari Okamoto is an academic researcher from Vaccine Research Center. The author has contributed to research in topics: Viral load & Lentivirus. The author has an hindex of 1, co-authored 1 publications receiving 1225 citations.
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HIV preferentially infects HIV-specific CD4 + T cells
Daniel C. Douek,Jason M. Brenchley,Michael R. Betts,David R. Ambrozak,Brenna J. Hill,Yukari Okamoto,Joseph P. Casazza,Janaki Kuruppu,Kevin J. Kunstman,Steven M. Wolinsky,Zvi Grossman,Zvi Grossman,Mark Dybul,Annette Oxenius,David Price,Mark Connors,Richard A. Koup +16 more
TL;DR: The findings show that HIV-specific CD4+ T cells are preferentially infected by HIV in vivo, which provides a potential mechanism to explain the loss of HIV- specific CD4- T-cell responses, and consequently theloss of immunological control of HIV replication.