Yukihito Kabuyama

TL;DR: This study showed that peptides which are larger than tripeptide could reach to the circulation system after administration of CH, revealing previously unknown dynamics of absorption of CH.

TL;DR: It is demonstrated that PO is an antidepressant bioactive peptide accompanying the proliferation of hippocampal neural progenitor cells in vivo and in vitro, and may be the mechanism for antidepressant‐like behavior.

TL;DR: Oral administration of ginger-degraded collagen hydrolysate (GDCH) significantly decreased depression-like behavior in a forced swim test, suggesting that GDCH exhibited antidepressant activity in mice, and increased GDNF and CNTF expression in the stressed condition, implying that mechanisms of the antidepressant activity of GDCH were the same in unstressed and stressed conditions.

TL;DR: HPLC-based purification coupled with MS, NMR analysis revealed that baicalin, a major flavone in SR, stimulates endothelial NO generation, suggesting its potential as an ingredient in medicinal food and beverage to treat hypertension.

TL;DR: The effects of APP hydrolysate digested artificially with pepsin and pancreatin on white adipose tissue and skeletal muscle are examined to suggest that the effect of APP on anti-obesity and muscle hypertrophy may be induced by peptides released from APP in the gastrointestinal tract.