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Yukio Suzuki
Researcher at Kitasato University
Publications - 74
Citations - 1410
Yukio Suzuki is an academic researcher from Kitasato University. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 21, co-authored 74 publications receiving 1337 citations. Previous affiliations of Yukio Suzuki include Stanford University & Keio University.
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Journal ArticleDOI
Hypercapnic Acidosis Attenuates Endotoxin-Induced Nuclear Factor-κB Activation
Kei Takeshita,Yukio Suzuki,Kazumi Nishio,Osamu Takeuchi,Kyoko Toda,Hiroyasu Kudo,Naoki Miyao,Makoto Ishii,Nagato Sato,Katsuhiko Naoki,Takuya Aoki,Koichi Suzuki,Rika Hiraoka,Kazuhiro Yamaguchi +13 more
TL;DR: It is concluded that hypercapnic acidosis would have anti-inflammatory effects essentially through a mechanism inhibiting NF-B activation, leading to downregulation of intercellular adhesion molecule-1 and interleukin-8, which in turn inhibits neutrophil adherence to pulmonary endothelial cells.
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Granulocyte colony-stimulating factor does not enhance endotoxin-induced acute lung injury in guinea pigs.
TL;DR: Pretreatment with G-CSF tended to attenuate rather than enhance neutrophil-dependent acute lung responses to endotoxin, which was similar to that in the CPA+endotoxin group.
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Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs.
TL;DR: It is concluded that the NADPH oxidase inhibitor apocynin attenuates sepsis-induced lung injury in guinea pigs, neutrophils ROS generation measured by CL, and neutrophil-mediated HUVEC injury assessed by 51Cr release.
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Inhibition of c-Jun NH2-Terminal Kinase Activity Improves Ischemia/Reperfusion Injury in Rat Lungs
Makoto Ishii,Yukio Suzuki,Kei Takeshita,Naoki Miyao,Hiroyasu Kudo,Rika Hiraoka,Kazumi Nishio,Nagato Sato,Katsuhiko Naoki,Takuya Aoki,Kazuhiro Yamaguchi +10 more
TL;DR: In conclusion, JNK plays a pivotal role in mediating lung injury caused by I/R, and inhibition of JNK activity has potential as an effective therapeutic strategy for preventing I-R injury during lung transplantation.
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Simultaneous measurement of pazufloxacin, ciprofloxacin, and levofloxacin in human serum by high-performance liquid chromatography with fluorescence detection.
Satoshi Watabe,Yoshiaki Yokoyama,Kazuyuki Nakazawa,Kimikazu Shinozaki,Rika Hiraoka,Kei Takeshita,Yukio Suzuki +6 more
TL;DR: The proposed method proved to be simple and reliable for the determination of three fluoroquinolones by high-performance liquid chromatography (HPLC) method with fluorescence detection with mean recoveries of pazufloxacin, ciprofloxacsin, and levofloxacIn.