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Yulan Lu
Researcher at Fudan University
Publications - 69
Citations - 751
Yulan Lu is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Exome sequencing. The author has an hindex of 11, co-authored 50 publications receiving 374 citations. Previous affiliations of Yulan Lu include Beijing Normal University & Boston Children's Hospital.
Papers
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Journal ArticleDOI
lncRNA Functional Networks in Oligodendrocytes Reveal Stage-Specific Myelination Control by an lncOL1/Suz12 Complex in the CNS
Danyang He,Danyang He,Jincheng Wang,Jincheng Wang,Yulan Lu,Yaqi Deng,Chuntao Zhao,Lingli Xu,Lingli Xu,Yinhuai Chen,Yueh Chiang Hu,Wenhao Zhou,Q. Richard Lu,Q. Richard Lu,Q. Richard Lu +14 more
TL;DR: A key lncRNA epigenetic circuitry through interaction with chromatin-modifying complexes in control of CNS myelination and myelin repair is revealed.
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Clinical and genetic spectrum of a large cohort of children with epilepsy in China.
Lin Yang,Yanting Kong,Xinran Dong,Liyuan Hu,Yifeng Lin,Xiang Chen,Qi Ni,Yulan Lu,Bingbing Wu,Huijun Wang,Q. Richard Lu,Wenhao Zhou +11 more
TL;DR: The 12 most commonly implicated genes in this cohort and the genes with treatment options should be considered as part of the essential panel for early diagnosis of epilepsy onset, if large medical exome analyses or ES are not feasible as first-tier analysis.
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SPRINT: an SNP-free toolkit for identifying RNA editing sites.
TL;DR: A novel method named SPRINT is presented that identifies RNA editing sites without the need to filter out SNPs and also integrates the detection of hyper RESs from remapped reads, and has been fully automated to any RNA‐seq data with reference genome sequence available.
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Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort
Xinran Dong,Bo Liu,Lin Yang,Huijun Wang,Bingbing Wu,Renchao Liu,Hongbo Chen,Xiang Chen,Sha Yu,Bin Chen,Sujuan Wang,Xiu Xu,Wenhao Zhou,Yulan Lu +13 more
TL;DR: With a higher diagnostic rate, more comprehensive observation of variations and lower cost compared with conventional strategies, simultaneous analysis of CNVs and SNVs based on CES showed potential as a new first-tier choice to diagnose DD.
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Optimized trio genome sequencing (OTGS) as a first-tier genetic test in critically ill infants: practice in China.
Huijun Wang,Yulan Lu,Xinran Dong,Guoping Lu,Guoqiang Cheng,Yanyan Qian,Qi Ni,Ping Zhang,Lin Yang,Bingbing Wu,Wenhao Zhou +10 more
TL;DR: High-capacity OTGS testing in detecting SNVs and chromosomal abnormalities with fast response, higher diagnostic yield, and lower cost demonstrates the potential to be the first-tier of genetic testing used in critically ill infants in developing countries.