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Yuming Cheng
Researcher at Fudan University
Publications - 9
Citations - 357
Yuming Cheng is an academic researcher from Fudan University. The author has contributed to research in topics: Internal medicine & HBsAg. The author has an hindex of 4, co-authored 5 publications receiving 314 citations. Previous affiliations of Yuming Cheng include Fudan University Shanghai Medical College.
Papers
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Journal ArticleDOI
Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients
Zhiao Chen,Yuming Cheng,Yongfen Xu,Jing Liao,Xiaonan Zhang,Yunwen Hu,Qin Zhang,Jiefei Wang,Zhanqing Zhang,Fang Shen,Zhenghong Yuan +10 more
TL;DR: This study reveals a possible interaction between HBsAg, TLR signaling and the innate immune response, which may partially explain the mechanism of HBV infection induced immuno-tolerance.
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Hepatitis B Virus Surface Antigen Selectively Inhibits TLR2 Ligand–Induced IL-12 Production in Monocytes/Macrophages by Interfering with JNK Activation
Sen Wang,Zhiao Chen,Zhiao Chen,Conghua Hu,Fangxing Qian,Yuming Cheng,Min Wu,Bisheng Shi,Jieliang Chen,Yunwen Hu,Zhenghong Yuan +10 more
TL;DR: It is demonstrated that HBsAg selectively inhibits Pam3csk4- stimulated IL-12 production in M/MΦs by blocking the JNK–MAPK pathway and provide a mechanism by which HBV evades immunity and maintains its persistence.
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Measles virus infection in adults induces production of IL-10 and is associated with increased CD4+ CD25+ regulatory T cells.
Xuelian Yu,Yuming Cheng,Bisheng Shi,Fangxing Qian,Feng-bin Wang,Xinian Liu,Hai-ying Yang,Qing-nian Xu,Tang-kai Qi,Li-jun Zha,Zhenghong Yuan,Reena Ghildyal +11 more
TL;DR: The results show that adult measles patients in the acute phase of the disease have a mixed Th1/Th2 type response, accompanied with severe immunosuppression of both innate and adaptive responses including suppression of type I IFN.
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Whole recombinant Hansenula polymorpha expressing hepatitis B virus surface antigen (yeast-HBsAg) induces potent HBsAg-specific Th1 and Th2 immune responses
Guanglin Bian,Yuming Cheng,Zekun Wang,Yunwen Hu,Xiaonan Zhang,Min Wu,Zhiao Chen,Bisheng Shi,Shuhui Sun,Yan Shen,Er jia Chen,Xin Yao,Yu-Mei Wen,Zhenghong Yuan +13 more
TL;DR: Temperature-killed whole recombinant Hansenula polymorpha yeast expressing hepatitis B surface antigen (yeast-HBsAg) was generated, and the immune responses elicited by yeast- HBsAg were investigated in mice, suggesting that yeast-HBSAg may be an ideal candidate for an effective vaccine for the control of chronic hepatitis B virus (HBV) infection.
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Metabolic associated fatty liver disease better identifying patients at risk of liver and cardiovascular complications
TL;DR: A nomenclature of metabolic associated fatty liver disease (MAFLD) with a new definition was proposed in 2020 instead of the previous "non-alcoholic fatty liver diseases" (NAFLD), whether it better coheres with the clinical demand remains controversial as mentioned in this paper .