Y
Yun Cheng
Publications - 5
Citations - 387
Yun Cheng is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications receiving 315 citations.
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Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance
Xiangnan Zhang,Haijing Yan,Yang Yuan,Jieqiong Gao,Zhe Shen,Yun Cheng,Yao Shen,Rong-rong Wang,Xiao-fen Wang,Weiwei Hu,Guanghui Wang,Zhong Chen +11 more
TL;DR: Autophagy was activated in the reperfusion phase, as revealed in both mice with middle cerebral artery occlusion and oxygen-glucose deprived cortical neurons in culture, and the protective role of autophagy during reperfusions may be attributable to mitophagy-related mitochondrial clearance and inhibition of downstream apoptosis.
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Emerging role of UFMylation in secretory cells involved in the endocrine system by maintaining ER proteostasis
TL;DR: In this paper , the authors summarized the core enzymes and factors involved in the UFMylation cascade, which, similar to ubiquitin, is consecutively catalyzed by UFM-activating enzyme 5 (UBA5), UFM1-conjugating enzyme 1 (UFC1), and UFM 1-specific ligase 1 (UFL1).
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A neuroprotective role of Ufmylation through Atg9 in the aging brain of Drosophila
Huifang Li,Zhenghong Yu,Zikang Niu,Yun Cheng,Zhenhao Wei,Yafei Cai,Fei Ma,Lanxin Hu,Weibo Zhang +8 more
TL;DR: In this paper , the Ufm1 system ensures the health of aged neurons via Atg9 by coordinating autophagy and mTORC1, and maintaining mitochondrial homeostasis and JNK activity.
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Flavokawain mitigates Ovalbumin (OVA)-induced asthma by regulating NLRP3 inflammasome and inflammatory markers: in-vitro and in-vivo models
TL;DR: In this article , the potential of flavokawain on the IL-4-induced 16HBE cell line and the ovalbumin (OVA)-induced mouse model was analyzed.
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Weighted gene coexpression network analysis reveals negative regulation of hypertrophic cardiomyopathy by carboxylesterase 1 and cathepsin C.
TL;DR: In this article , a weighted gene co-expression network analysis (WGCNA) was performed on ribonucleic acid (RNA) sequence data of myocardial tissue in hypertrophic cardiomyopathy (HCM) patients and found that the expression of carboxylesterase 1 (CES1) and cathepsin C (CTSC) negatively correlated with Maxi LVWT.