Y
Yun Jeong Kim
Researcher at Chung-Ang University
Publications - 26
Citations - 544
Yun Jeong Kim is an academic researcher from Chung-Ang University. The author has contributed to research in topics: Programmed cell death & Reactive oxygen species. The author has an hindex of 13, co-authored 26 publications receiving 487 citations.
Papers
More filters
Journal ArticleDOI
18β-Glycyrrhetinic acid induces apoptotic cell death in SiHa cells and exhibits a synergistic effect against antibiotic anti-cancer drug toxicity
TL;DR: Results suggest that 18beta-glycyrrhetinic acid may cause cell death in SiHa cells by inducing the mitochondrial membrane permeability change, leading to cytochrome c release and caspase-3 activation, which may be associated with increased formation of reactive oxygen species and depletion of glutathione.
Journal ArticleDOI
Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death.
TL;DR: The results show that lamotrigine seems to reduce the cytotoxicity of rotenone and MPP+ by suppressing the mitochondrial permeability transition formation, leading to cytochrome c release and subsequent activation of caspase-3.
Journal ArticleDOI
Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways.
Chung Soo Lee,Sang Won Kwak,Yun Jeong Kim,Seon Ae Lee,Eon Sob Park,Soon Chul Myung,Wonyong Kim,Min Sung Lee,Jeong Jae Lee +8 more
TL;DR: YC-1 may potentiate the apoptotic effect of licochalcone A on ovarian carcinoma cell lines by increasing the activation of the caspase-8- and Bid-dependent pathway and the mitochondria-mediated apoptotic pathway, leading to caspases activation.
Journal ArticleDOI
Prevention of 7-ketocholesterol-induced mitochondrial damage and cell death by calmodulin inhibition
TL;DR: Calmodulin inhibition may exhibit a protective effect against the neurotoxicity of 7-ketocholesterol by suppressing formation of the mitochondrial permeability transition, leading to the release of cytochrome c and subsequent activation of caspase-3.
Journal ArticleDOI
Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins.
TL;DR: It is suggested that radicicol may potentiate the apoptotic effect of TRAIL on ovarian carcinoma cell lines by increasing the activation of the caspase-8- and Bid-dependent pathway and the mitochondria-mediated apoptotic pathway, leading to caspases activation.