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Yunli Xie

Researcher at Fudan University

Publications -  19
Citations -  1245

Yunli Xie is an academic researcher from Fudan University. The author has contributed to research in topics: Progenitor cell & Neurogenesis. The author has an hindex of 12, co-authored 18 publications receiving 1114 citations. Previous affiliations of Yunli Xie include Austrian Academy of Sciences & Medical University of Vienna.

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The GTP-binding protein Septin 7 is critical for dendrite branching and dendritic-spine morphology.

TL;DR: It is shown that Septin 7 (Sept7) localizes at the bases of filopodia and at branch points in developing hippocampal neurons and that Sept5 and Sept11 colocalize with and coimmunoprecipitate with Sept7, thereby arguing for the existence of a Septin5/7/11 complex.
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Dendritic Localization of the Translational Repressor Pumilio 2 and Its Contribution to Dendritic Stress Granules

TL;DR: It is found that Pum2 mRNA is expressed during neuronal development and that the protein is found in discrete particles in both the cell body and the dendritic compartment of fully polarized neurons, indicating that Pumar2 is a novel candidate of dendritically localized ribonucleoparticles (RNPs).
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Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

TL;DR: The results indicate that the orientation of progenitor cell divisions is important for correct lineage specification in the developing mammalian brain and suggest that oblique divisions are essential for generating the correct numbers of neurons in all cortical layers.
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High-efficiency transfection of mammalian neurons via nucleofection

TL;DR: Using the recently developed 96-well shuttle system, reproducible high-throughput expression of various transgenes is now feasible on primary neurons, for example large-scale RNAi analyses to downregulate gene expression.
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The brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesis

TL;DR: An important role is suggested for Stau2 in the formation and maintenance of dendritic spines of hippocampal neurons in down-regulated neurons.