Z
Zachary A. Costliow
Researcher at University of Illinois at Urbana–Champaign
Publications - 5
Citations - 76
Zachary A. Costliow is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Bacteroides & Bacteroides thetaiotaomicron. The author has an hindex of 2, co-authored 4 publications receiving 42 citations. Previous affiliations of Zachary A. Costliow include Broad Institute.
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Journal ArticleDOI
Thiamine Acquisition Strategies Impact Metabolism and Competition in the Gut Microbe Bacteroides thetaiotaomicron.
TL;DR: Thiamine acquisition mechanisms used by B. thetaiotaomicron not only are critical for its physiology and fitness but also provide the opportunity to model how other gut microbes may respond to the shifting availability of thiamine in the gut, adding further evidence that altering the presence or concentrations of water-soluble vitamins such as thiamines may be an effective method for manipulating gut community composition.
Journal ArticleDOI
pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells
Xiangjun Chen,Alok Jaiswal,Zachary A. Costliow,Paula Herbst,Elizabeth A. Creasey,Noriko Oshiro-Rapley,Mark J. Daly,Kimberly L. Carey,Daniel B. Graham,Ramnik J. Xavier +9 more
TL;DR: Xavier et al. as mentioned in this paper examined cell type-specific roles of the pH sensor G protein-coupled receptor 65 (GPR65) and its inflammatory disease-associated Ile231Leu-coding variant in inflammation control.
Journal ArticleDOI
A Novel Family of RNA-Binding Proteins Regulate Polysaccharide Metabolism in Bacteroides thetaiotaomicron.
Amanda N.D. Adams,Muhammad S. Azam,Zachary A. Costliow,Xiangqian Ma,Patrick H. Degnan,Carin K. Vanderpool +5 more
TL;DR: In this paper, a purified RNA-binding protein (RBP) from Bacteroides thetaiotaomicron was found to be able to bind to single-stranded RNA in vitro with an affinity similar to other characterized RBPs.
Posted ContentDOI
Thiamine pyrophosphate riboswitches inBacteroidesspecies regulate transcription or translation of thiamine transport and biosynthesis genes
TL;DR: The genetic basis of thiamine (Vitamin B1) uptake and biosynthesis in three representative Bacteroides species is investigated and implies that gut Bactseroides have evolved distinct strategies for making or acquiring an essential nutrient.
Posted ContentDOI
A Novel Family of RNA-Binding Proteins Regulate Polysaccharide Metabolism in Bacteroides thetaiotaomicron
Amanda N.D. Adams,Muhammad S. Azam,Muhammad S. Azam,Zachary A. Costliow,Zachary A. Costliow,Xiangqian Ma,Patrick H. Degnan,Carin K. Vanderpool +7 more
TL;DR: A purified RNA-binding protein (RBP) from Bacteroides thetaiotaomicron was found to have an affinity similar to other characterized regulatory RBPs.