Z
Zaher K. Otrock
Researcher at Cleveland Clinic
Publications - 113
Citations - 2766
Zaher K. Otrock is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Cancer & Factor V Leiden. The author has an hindex of 22, co-authored 109 publications receiving 2511 citations. Previous affiliations of Zaher K. Otrock include American University of Beirut & Mashhad University of Medical Sciences.
Papers
More filters
Journal ArticleDOI
Vascular endothelial growth factor family of ligands and receptors: review.
TL;DR: The biology of the VEGF ligands and the receptors is reviewed, including the receptors identified so far, and the neuropilins (NP-1 and NP-2).
Journal ArticleDOI
Understanding the biology of angiogenesis: review of the most important molecular mechanisms.
TL;DR: Vascular endothelial growth factor-A is the most potent pro-angiogenic protein described to date and may reveal new targets for treating many diseases that are associated with this complex process.
Journal ArticleDOI
Meta-Analysis on the Use of Zidovudine and Interferon-Alfa in Adult T-Cell Leukemia/Lymphoma Showing Improved Survival in the Leukemic Subtypes
Ali Bazarbachi,Yves Plumelle,Juan Carlos Ramos,Patricia Tortevoye,Zaher K. Otrock,Graham P. Taylor,Antoine Gessain,William J. Harrington,Gérard Panelatti,Olivier Hermine +9 more
TL;DR: A meta-analysis of antiviral therapy of ATL confirmed the high efficacy of AZT and IFN, which should now be considered the gold standard first-line therapy in leukemic subtypes of ATL.
Journal ArticleDOI
Thalassemia and hypercoagulability.
TL;DR: The molecular and cellular mechanisms leading to hypercoagulability in beta-thalassemia are reviewed, with a special focus on thalassemia intermedia being the group with the highest incidence of thrombotic events as compared to other types ofThalassemias.
Journal ArticleDOI
PRPF8 defects cause missplicing in myeloid malignancies
Amina Kurtovic-Kozaric,Bartlomiej P Przychodzen,Jarnail Singh,Maria M. Konarska,Michael J. Clemente,Zaher K. Otrock,Megan O. Nakashima,Eric D. Hsi,Kenichi Yoshida,Yuichi Shiraishi,Kenichi Chiba,Hirokazu Tanaka,Satoru Miyano,Seishi Ogawa,Jacqueline Boultwood,Hideki Makishima,Jaroslaw P. Maciejewski,Richard A. Padgett +17 more
TL;DR: The exploration of clinical and functional consequences suggests that PRPF8 is a novel leukemogenic gene in myeloid neoplasms with a distinct phenotype likely manifested through aberrant splicing.