Graham P. Taylor

TL;DR: Data show that the process of accumulation of escape mutations within HIV is not inevitable, and complex epitope- and residue-specific selection forces, including CTL-mediated positive selection pressure and virus-mediated purifying selection, operate in tandem to shape HIV evolution at the population level.

TL;DR: It is shown that cell contact rapidly induces polarization of the cytoskeleton of the infected cell to the cell-cell junction, and HTLV-I core (Gag protein) complexes and the HT LVI genome accumulate at thecell junction and are then transferred to the uninfected cell.

TL;DR: In this article, the authors investigated transmission and viral load kinetics in vaccinated and unvaccinated individuals with mild delta variant infection in the community, and found that faster viral load growth was correlated with higher peak viral load (correlation 0·42 [95% credible interval 0·13 to 0·65]) and slower decline (0·44 [−0·67 to −0·18]).

TL;DR: It is concluded that nitric oxide synthase in macula densa cells is activated by tubular-fluid reabsorption and mediates a vasodilating component to the tubuloglomerular feedback response.

TL;DR: A group of ATL researchers joined to form a consensus statement based on established data to define prognostic factors, clinical subclassifications, and treatment strategies, and a set of response criteria specific for ATL reflecting a combination of those for lymphoma and CLL was proposed.