Z
Zhe S Chen
Researcher at St. John's University
Publications - 61
Citations - 671
Zhe S Chen is an academic researcher from St. John's University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 2 publications receiving 19 citations.
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Journal ArticleDOI
Microbiota in health and diseases
Kaijian Hou,Zhuo-Xun Wu,Xuan-Yu Chen,Jing-Quan Wang,Dongya Zhang,Chuan Xiao,Dan Zhu,Jagadish B. Koya,Liuya Wei,Jilin Li,Zhe S Chen +10 more
TL;DR: The role of microbiota in health and diseases is highlighted by numerous studies since its discovery as mentioned in this paper , which can lead to dysregulation of bodily functions and diseases including cardiovascular diseases (CVDs), cancers, respiratory diseases, etc.
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m6A modification: recent advances, anticancer targeted drug discovery and beyond
Lijuan Deng,Weilun Deng,Shunming Fan,Minfeng Chen,Ming-Xiu Qi,Wen-Yu Lyu,Qi Qi,Amit K. Tiwari,Jiaxu Chen,Dong-Mei Zhang,Zhe S Chen +10 more
TL;DR: In this article , the authors provide an update of the latest findings on m6A modification and the critical roles of modification in cancer progression, and summarize rational sources for the discovery of M6A-targeted anticancer agents from traditional medicines and computer-based chemosynthetic compounds.
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Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma
Yuanjun Lu,Yau-Tuen Chan,Hor-Yue Tan,Sheng Zhang,Wei Guo,Yu Xu,Rakesh Sharma,Zhe S Chen,Yiqiong Zheng,Ning Wang,Yibin Feng +10 more
TL;DR: In this article , miR-23a-3p was found to be the most prominent miRNA in HCC, which was overexpressed in nonresponders and indicated poor survival and HCC relapse.
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The Single‐Cell Landscape of Intratumoral Heterogeneity and The Immunosuppressive Microenvironment in Liver and Brain Metastases of Breast Cancer
Yu-chao Zou,Feng Ye,Yanan Kong,Xiaoqian Hu,Xinpei Deng,Jindong Xie,Cailu Song,Xueqi Ou,Song Wu,Linyu Wu,Yi Xie,Wenwen Tian,Yu-Chien Tang,Chau Wei Wong,Zhe S Chen,Xinhua Xie,Hailin Tang +16 more
TL;DR: In this article , a high-resolution map of the entire tumor ecosystem based on 44 473 cells from breast cancer liver and brain metastases is depicted using single-cell RNA sequencing.
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Proteomics technologies for cancer liquid biopsies
TL;DR: A review of high-plex proteomics technologies that are capable of measuring at least hundreds of proteins simultaneously from liquid biopsy samples, ranging from traditional technologies based on mass spectrometry (MS) and antibody/antigen arrays to innovative methods based on aptamer, proximity extension assay (PEA), and reverse phase protein arrays (RPPA) is presented in this article .