Z
Zhen-Yang Gu
Researcher at Chinese PLA General Hospital
Publications - 33
Citations - 287
Zhen-Yang Gu is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Hematopoietic stem cell transplantation & Transplantation. The author has an hindex of 8, co-authored 28 publications receiving 219 citations. Previous affiliations of Zhen-Yang Gu include Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Efficacy of oral cryotherapy on oral mucositis prevention in patients with hematological malignancies undergoing hematopoietic stem cell transplantation: a meta-analysis of randomized controlled trials.
Li Wang,Zhen-Yang Gu,Rui-Ren Zhai,Sha-Sha Zhao,Lan Luo,Dandan Li,Xiao-Li Zhao,Hua-Ping Wei,Zhao-Xia Pang,Li-Li Wang,Dai-Hong Liu,Quan-Shun Wang,Chun-Ji Gao +12 more
TL;DR: Oral cryotherapy is a readily applicable and cost-effective prophylaxis for OM in patients undergoing HSCT, and the pooled results were uncertain for the duration of OM and analgesic use.
Journal ArticleDOI
Efficacy and safety of thrombopoietin receptor agonists in patients with primary immune thrombocytopenia: A systematic review and meta-analysis
Li Wang,Zhe Gao,Xiao-Ping Chen,Hai-Yan Zhang,Nan Yang,Fei-Yan Wang,Li-Xun Guan,Zhen-Yang Gu,Sha-Sha Zhao,Lan Luo,Hua-Ping Wei,Chun-Ji Gao +11 more
TL;DR: It is demonstrated that T PO-RAs are an effective and safe second-line treatment option for primary ITP patients and there was a significant reduction in the proportion of patients needing rescue medications in the TPO-RA groups compared with the control groups.
Journal ArticleDOI
Novel CD7-specific nanobody-based immunotoxins potently enhanced apoptosis of CD7-positive malignant cells
Jinle Tang,Jialu Li,Xuejun Zhu,Yuan Yu,Dan Chen,Lei Yuan,Zhen-Yang Gu,Xingding Zhang,Lin Qi,Zhishu Gong,Pengjun Jiang,Juhua Yu,Huimin Meng,Gangli An,Huyong Zheng,Lin Yang,Lin Yang +16 more
TL;DR: This CD7 nanobody-based immunotoxin exhibited a superior anti-CD7 positive malignancies activity than previously reported immunotoxins, and may represent a promising therapeutic strategy in treating CD7-positive leukemia and lymphoma, which still remain a significant clinical challenge.
Journal ArticleDOI
Efficacy and safety of mesenchymal stromal cells for the prophylaxis of chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: a meta-analysis of randomized controlled trials
Li Wang,Cheng-Ying Zhu,De-Xun Ma,Zhen-Yang Gu,Chang-Chun Xu,Fei-Yan Wang,Ji-Gang Chen,Liu Chengjun,Li-Xun Guan,Rui Gao,Zhe Gao,Shu Fang,Du-Jun Zhuo,Shu-Feng Liu,Chun-Ji Gao +14 more
TL;DR: It is demonstrated that MSC infusion is an effective and safe prophylactic strategy for cGVHD in patients with hematological malignancies undergoing allo-HSCT.
Journal ArticleDOI
Similar outcomes after haploidentical transplantation with post-transplant cyclophosphamide versus HLA-matched transplantation: a meta-analysis of case-control studies.
Zhen-Yang Gu,Li Wang,Lei Yuan,Wenrong Huang,Meng Li,Li-Xun Guan,Qingyi Wang,Zhe Gao,Sha-Sha Zhao,Lan Luo,Fei-Yan Wang,Nan Yang,Dai-Hong Liu,Jon C. Aster,Chun-Ji Gao +14 more
TL;DR: It is suggested that haplo-HCT with PT-Cy can achieve comparable outcomes with those of HLA-matched HCT, and Haploidentical donors can be a feasible and valid alternative when conventional H LA-matched donors are unavailable.