Z
Zhen Zhang
Researcher at Johns Hopkins University
Publications - 224
Citations - 16297
Zhen Zhang is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 57, co-authored 189 publications receiving 13444 citations. Previous affiliations of Zhen Zhang include Medical University of South Carolina & Children's National Medical Center.
Papers
More filters
Journal ArticleDOI
KDDN: an open-source Cytoscape app for constructing differential dependency networks with significant rewiring
Ye Tian,Bai Zhang,Eric P. Hoffman,Robert Clarke,Zhen Zhang,Ie-Ming Shih,Jianhua Xuan,David M. Herrington,Yue Joseph Wang +8 more
TL;DR: The acquired biologically plausible results provide new insights into network rewiring as a mechanistic principle and illustrate the performance of KDDN on various simulations and real gene expression datasets, and further compare the results with those obtained by the most relevant peer methods.
Patent
Biomarkers for breast cancer
TL;DR: In this paper, protein-based biomarkers and biomarker combinations were used to classify a subject sample as breast cancer or non-breast cancer, and the biomarkers can be detected by SELDI mass spectrometry.
Posted Content
OmicsMapNet: Transforming omics data to take advantage of Deep Convolutional Neural Network for discovery.
Shiyong Ma,Zhen Zhang +1 more
TL;DR: OmicsMapNet approach to take advantage of existing deep leaning frameworks to analyze high-dimensional omics data as 2-dimensional images to capture the functional hierarchical structure of genes in 2D images.
Journal ArticleDOI
Comparison of 3 Paclitaxel-Based Chemoradiotherapy Regimens for Patients With Locally Advanced Esophageal Squamous Cell Cancer
Dashan Ai,Jinjun Ye,Shihong Wei,Yunhai Li,Hui Lu,Jinbin Cao,Zhengfei Zhu,Weixin Zhao,Qin Lin,Huan-Jun Yang,Xiangpeng Zheng,Jialiang Zhou,Guang Huang,Lin Li,Tiancheng Li,Zhibo Zhang,Guoren Zhou,Dayong Gu,Mingyu Du,Miao Mo,Huixun Jia,Zhen Zhang,Kuaile Zhao +22 more
TL;DR: The pac litaxel plus fluorouracil regimen did not show overall survival superiority over paclitaxel regimens with cisplatin or carboplatin in patients with locally advanced esophageal squamous cell carcinoma who are in chemoradiation therapy.
Journal ArticleDOI
Urinary glycoproteins associated with aggressive prostate cancer.
Mingming Dong,T. Mamie Lih,Shao Yung Chen,Kyung Cho Cho,Rodrigo Vargas Eguez,Naseruddin Höti,Yangying Zhou,Weiming Yang,Leslie A. Mangold,Daniel W. Chan,Zhen Zhang,Lori J. Sokoll,Alan W. Partin,Hui Zhang +13 more
TL;DR: Glyopeptides of urinary glycoproteins associated with aggressive prostate cancer are identified using a quantitative mass spectrometry-based glycoproteinomic approach and demonstrated their potential to serve as noninvasive urinary Glycoprotein biomarkers worthy of further validation by a multi-center study.