Z
Zhengnian Ding
Researcher at Nanjing Medical University
Publications - 65
Citations - 1604
Zhengnian Ding is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Protein kinase B & Heat shock protein. The author has an hindex of 21, co-authored 61 publications receiving 1324 citations. Previous affiliations of Zhengnian Ding include Kanazawa University.
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Journal ArticleDOI
Anesthesia for electroconvulsive therapy.
Zhengnian Ding,Paul F. White +1 more
TL;DR: An update on the anesthetic management of patients undergoing ECT is provided to understand the physiologic responses to the electrical stimulus, the effect of anesthetic drugs on the ECT response, and the pharmacologic effects of the drugs used to attenuate the side effects related to ECT.
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Dexamethasone attenuated bupivacaine-induced neuron injury in vitro through a threonine-serine protein kinase B-dependent mechanism.
TL;DR: The data suggest that pretreatment of neuroblastoma cells with dexamethasone exerts a protective effect on bupivacaine-induced neuronal cell injury, and the mechanisms involve activating the Akt signaling pathway.
Journal ArticleDOI
Involvement of Reductive Stress in the Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Heat Shock Protein 27
Xia Zhang,Xiao-yan Min,Chuanfu Li,Ivor J. Benjamin,Bo Qian,Xiaojin Zhang,Zhengnian Ding,Xiang Gao,Yuzhen Yao,Yujie Ma,Yunling Cheng,Li Liu +11 more
TL;DR: The data indicate that the Hsp27-induced cardiomyopathy could be attributed to, at least in part, upregulation of glutathione peroxidase 1, and suggest that HSp27 may serve as a potential target for the treatment of patients with carduomyopathy.
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Essential role of ERK activation in neurite outgrowth induced by α-lipoic acid
Xiaohui Wang,Zhuyao Wang,Zhuyao Wang,Yuzhen Yao,Jingjin Li,Xiaojin Zhang,Chuanfu Li,Yunlin Cheng,Guoxian Ding,Li Liu,Zhengnian Ding +10 more
TL;DR: The data suggest that LA stimulates neurite outgrowth through the activation of ERK signaling, an effect mediated through a ROS-dependent mechanism.
Journal ArticleDOI
Attenuation of cardiac dysfunction by HSPA12B in endotoxin-induced sepsis in mice through a PI3K-dependent mechanism.
Hongmei Zhou,Jin Qian,Chuanfu Li,Jingjin Li,Xiaojin Zhang,Zhengnian Ding,Xiang Gao,Zhihua Han,Yunlin Cheng,Li Liu +9 more
TL;DR: It is suggested that HSPA12B plays an important role in the attenuation of endotoxin-induced cardiac dysfunction and that the mechanisms involve the preserved activation of PI3K/Akt signalling, resulting in attenuated of LPS-increased expression of VCAM-1/ICAM- 1 and leucocyte infiltration into the myocardium.