Z
Zhi-Wen Fang
Researcher at Harbin Medical University
Publications - 1
Citations - 1398
Zhi-Wen Fang is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Pharmacokinetics & Acute promyelocytic leukemia. The author has an hindex of 1, co-authored 1 publications receiving 1345 citations.
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Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients
Zhi-Xiang Shen,Guo-Qiang Chen,Jian-Hua Ni,Xiu-Shong Li,Shu-Min Xiong,Qian-Yao Qiu,Jun Zhu,Wei Tang,Guan-Lin Sun,Kan-Qi Yang,Yu Chen,Li Zhou,Zhi-Wen Fang,Yan-Ting Wang,Jun Ma,Peng Zhang,Ting-Dong Zhang,Sai-Juan Chen,Zhu Chen,Zhen-Yi Wang +19 more
TL;DR: As2O3 treatment is an effective and relatively safe drug in APL patients refractory to ATRA and conventional chemotherapy, and Pharmacokinetic studies showed that after a peak level of 5.54 micromol/L, plasma arsenic was rapidly eliminated, and the continuous administration of As2O2 did not alter its pharmacokinetic behaviors.