Z
Zhi-Xuan Li
Researcher at Sun Yat-sen University
Publications - 13
Citations - 484
Zhi-Xuan Li is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Nasopharyngeal carcinoma & Medicine. The author has an hindex of 5, co-authored 7 publications receiving 184 citations.
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Journal ArticleDOI
Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3
Zi-Qi Zheng,Zhi-Xuan Li,Guan-Qun Zhou,Li Lin,Lu-Lu Zhang,Jia-Wei Lv,Xiao-Dan Huang,Rui-Qi Liu,Fo-Ping Chen,Xiao-Jun He,Jia Kou,Jian Zhang,Jian Zhang,Xin Wen,Ying-Qin Li,Jun Ma,Na Liu,Ying Sun +17 more
TL;DR: A potential ceRNA regulatory pathway in which FAM225A modulates ITGB3 expression by binding to miR-590-3p and miR -1275, ultimately promoting tumorigenesis and metastasis in NPC is revealed.
Journal ArticleDOI
Comprehensive characterization of the alternative splicing landscape in head and neck squamous cell carcinoma reveals novel events associated with tumorigenesis and the immune microenvironment.
Zhi-Xuan Li,Zi-Qi Zheng,Zhuo-Hui Wei,Lu-Lu Zhang,Feng Li,Li Lin,Rui-Qi Liu,Xiao-Dan Huang,Jia-Wei Lv,Fo-Ping Chen,Xiao-Jun He,Jia-Li Guan,Jia Kou,Jun Ma,Guan-Qun Zhou,Ying Sun +15 more
TL;DR: This comprehensive genome-wide analysis of the AS landscape in HNSC revealed novel AS events related to carcinogenesis and immune microenvironment, with implications for prognosis and therapeutic responses.
Journal ArticleDOI
Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance.
Zi-Qi Zheng,Zhi-Xuan Li,Jia-Li Guan,Xu Liu,Jun-Yan Li,Yue Chen,Li Lin,Jia Kou,Jia-Wei Lv,Lu-Lu Zhang,Guan-Qun Zhou,Rui-Qi Liu,Fo-Ping Chen,Xiao-Jun He,Ying-Qin Li,Feng Li,Si-Si Xu,Jun Ma,Na Liu,Ying Sun +19 more
TL;DR: It is demonstrated that TINCR acts as a crucial driver of NPC progression and chemoresistance and highlights the newly identified TIN CR–ACLY–PADI1–MAPK–MMP2/9 axis as a potential therapeutic target in NPC.
Journal ArticleDOI
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis
Zhi-Xuan Li,Zi-Qi Zheng,Pau Chyu Yang,Li Li,Guan-Qun Zhou,Jia-Wei Lv,Lu-Lu Zhang,Ying-Qin Li,Chen-Fei Wu,Feng Li,Jun Ma,Na Liu,Ying Sun +12 more
TL;DR: It is shown that Wilms' tumor 1-associating protein (WTAP) expression was apparently upregulated in NPC, and increased WTAP was associated with poor prognosis, and WTAP-mediated DIAPH1-AS1 m6A methylation is required for NPC tumorigenesis and metastasis.
Journal ArticleDOI
Prognostic potential of liquid biopsy tracking in the posttreatment surveillance of patients with nonmetastatic nasopharyngeal carcinoma
Fo-Ping Chen,Xiao-Dan Huang,Jia-Wei Lv,Dan-Wan Wen,Guan-Qun Zhou,Li Lin,Jia Kou,Chen-Fei Wu,Yue Chen,Zi-Qi Zheng,Zhi-Xuan Li,Xiao-Jun He,Ying Sun +12 more
TL;DR: The current study was performed to investigate whether circulating cell‐free Epstein‐Barr virus DNA (cfEBV DNA) would be useful for posttreatment surveillance in patients with nasopharyngeal carcinoma (NPC).