Solid phase sensitive palladium(II) ions detection and recovery using ligand based efficient conjugate nanomaterials

5.3. Aromatic Ring Formation 1576 5.3.1. One Substituent at C-2 1576 5.3.2. Two Substituents at C-2 and C-3 1577 5.3.3. Two Substituents at C-2 and C-5 1577 5.3.4. Two Substituents at C-3 and C-4 1577 5.3.5. Three Substituents at C-2, C-3, and C-4 1578 5.3.6. Four Substituents at Carbon Atoms 1579 5.3.7. Benzotriazolyl Substituent at the Ring 1579 6. Furan 1580 6.1. Nonaromatic Rings 1580 6.1.1. Tetrahydrofurans 1580 6.1.2. 2,5-Dihydrofurans 1580 6.2. Electrophilic Substitution of the Aromatic Ring 1581 6.3. Aromatic Ring Formation 1582 7. Thiophene 1583 7.1. Nonaromatic Rings 1583 7.2. Electrophilic Substitution of the Aromatic Ring 1583 7.3. Aromatic Ring Formation 1583 8. Five-Membered Rings with Two Heteroatoms 1584 8.1. Pyrazole 1584 8.2. Imidazole 1586 8.3. Isoxazole 1589 8.4. Oxazole 1590 8.5. Thiazole 1592 9. Five-Membered Rings with Three or Four Heteroatoms 1594

Synthesis of Heterocycles Mediated by Benzotriazole. 1. Monocyclic Systems

Data published in the last 10 years on the use of the aza-Michael reaction in organic synthesis are described systematically. The attention is focused on environmentally friendly processes following green chemistry principles and on methods for the synthesis of compounds that are difficult to access by other routes.

https://iopscience.iop.org/article/10.1070/RC2011v080n03ABEH004162/pdf

Aza-Michael reaction: achievements and prospects

Carbon monoxide (CO) is an important gasotransmitter in living systems and its fluorescent detection is of particular interest. However, fluorescent detection of CO in living cells is still challenging due to lack of effective probes. In this paper, a readily available fluorescein-based fluorescent probe was developed for rapid detection of CO. This probe can be used to detect CO in almost wholly aqueous solution under mild conditions and shows high selectivity and sensitivity for CO with colorimetric and remarkable fluorescent turn-on signal changes. The detection limit of this probe for CO is as low as 37 nM with a linear range of 0–30 μM. More importantly, this probe (1 μM dose) can be conveniently used for fluorescent imaging CO in living cells.

Readily Available Fluorescent Probe for Carbon Monoxide Imaging in Living Cells

Elucidating the internal relationship between diseases and mitochondrial viscosity remains a great challenge due to the lack of the studies on multidisease living animals. So far, demonstrating abnormal mitochondria viscosity in the fatty liver and tumor living mice has not been achieved. To address this critical challenge, the powerful two-photon and mitochondria-targeted fluorescence probe CBI-V was designed herein for viscosity detection with deep red emission. Utilizing the new probe CBI-V, the mitochondrial viscosity alteration in living systems caused by monensin or nystatin has been monitored sensitively and selectively in real time. Moreover, the probe is capable of imaging mitochondrial viscosity in the inflammatory models at the cell, zebrafish, and mice level. Importantly, the visualization of mitochondrial viscosity has been achieved in both fatty liver and tumor living mice for the first time. This work not only advances the study of the relationship between disease and mitochondrial viscosity but also opens up an efficient way for diagnosing mitochondrial viscosity related diseases.

Visualization of Mitochondrial Viscosity in Inflammation, Fatty Liver, and Cancer Living Mice by a Robust Fluorescent Probe.

A novel colorimetric and fluorescent probe for the highly selective and sensitive detection of palladium based on Pd(0) mediated reaction

Features and applications of reactions of α,β-unsaturated N-acylbenzotriazoles with amino compounds

Novel A–π–D–π–A type molecules based on diphenylamine and carbazole with large two-photon absorption cross section and excellent aggregation-induced enhanced emission property

Two sensors based on π-extended TTF: synthesis and high selectivity for copper(II)

The acylation of Se-nucleophiles with N-acylbenzotriazoles was investigated. Samarium phenylselenolate and benzylselenolate (RSeSmI2) reacted with N-aroyl and N-alkanoylbenzotriazoles smoothly and afforded the corresponding selenol esters in good yields. Treatment of the RSeSmI2 with α,β-unsaturated N-acylbenzotriazoles afforded the anticipated α,β-unsaturated selenol esters in moderate yields, due mainly to the side reaction of conjugate addition. GRAPHICAL ABSTRACT

Zhifang Li

Papers

A novel colorimetric and fluorescent probe for the highly selective and sensitive detection of palladium based on Pd(0) mediated reaction

Features and applications of reactions of α,β-unsaturated N-acylbenzotriazoles with amino compounds

Novel A–π–D–π–A type molecules based on diphenylamine and carbazole with large two-photon absorption cross section and excellent aggregation-induced enhanced emission property

Two sensors based on π-extended TTF: synthesis and high selectivity for copper(II)

Investigation on the Se-Acylation with N-Acylbenzotriazoles