Zhixiang Zhou

TL;DR: The obtained data suggest that co-delivery of DOX and miR-34a could achieve synergistic effects on tumor suppression and nanosystem-based co-Delivery of tumor suppressive miRNAs and chemotherapeutic agents may be a promising combined therapeutic strategy for enhanced anti-tumor therapy.

TL;DR: It is shown that overexpression of miR-203 in esophageal cancer cells dramatically increased cell apoptosis and inhibited cell proliferation, migration and invasion as well as tumor growth and down-regulated miR -21 expression, and small GTPase Ran was a target gene of mi R-203.

TL;DR: Human bronchial epithelial cells exposed to various concentrations of particles smaller than 2.5 μm collected from Beijing, China induced a large number of genes involved in responses to xenobtiotic stimuli, metabolic response, and inflammatory and immune response pathways, which might contribute to PM2.5-related pulmonary diseases.

TL;DR: In vitro and in vivo experiments illustrate that HP‐IPECs have a great potential as a biodegradable vector for microRNA‐based therapy against triple‐negative breast cancer.

TL;DR: Collagen hydrogel can provide an appropriate 3-D environment for the chondrogenesis of UC-MSCs, which possess the capacity to differentiate along osteogenic lineage and have great potential for cartilage engineering.