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Showing papers by "Ziad Francis published in 2012"

Journal Article•DOI•
Monte Carlo simulation of energy-deposit clustering for ions of the same LET in liquid water

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Ziad Francis1, Sebastien Incerti2, Vladimir Ivanchenko, Christophe Champion3, M. Karamitros2, Mario A. Bernal4, Z. El Bitar •
Saint Joseph University1, University of Bordeaux2, Metz3, State University of Campinas4
07 Jan 2012-Physics in Medicine and Biology
TL;DR: A Monte Carlo study of energy depositions due to protons, alpha particles and carbon ions of the same linear-energy-transfer (LET) in liquid water using the Geant4-DNA toolkit and an adapted version of the DBSCAN clustering algorithm.
Abstract: This work presents a Monte Carlo study of energy depositions due to protons, alpha particles and carbon ions of the same linear-energy-transfer (LET) in liquid water. The corresponding track structures were generated using the Geant4-DNA toolkit, and the energy deposition spatial distributions were analyzed using an adapted version of the DBSCAN clustering algorithm. Combining the Geant4 simulations and the clustering algorithm it was possible to compare the quality of the different radiation types. The ratios of clustered and single energy depositions are shown versus particle LET and frequency-mean lineal energies. The estimated effect of these types of radiation on biological tissues is then discussed by comparing the results obtained for different particles with the same LET.

52 citations

Journal Article•DOI•
Combination of electromagnetic physics processes for microdosimetry in liquid water with the Geant4 Monte Carlo simulation toolkit

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Vladimir Ivanchenko, Sebastien Incerti1, Ziad Francis2, H.N. Tran1, M. Karamitros1, Mario A. Bernal3, Christophe Champion1, Christophe Champion4, Paul Gueye5 •
University of Bordeaux1, Saint Joseph University2, State University of Campinas3, Metz4, Hampton University5
15 Feb 2012-Nuclear Instruments & Methods in Physics Research Section B-beam Interactions With Materials and Atoms
TL;DR: The Geant4 Monte Carlo simulation toolkit provides a set of electromagnetic physics processes adapted to the detailed simulation of particle interactions in liquid water for microdosimetry applications, such as single-cell irradiation with light ion beams as mentioned in this paper.
Abstract: The Geant4 Monte Carlo simulation toolkit provides a set of electromagnetic physics processes adapted to the detailed simulation of particle interactions in liquid water for microdosimetry applications, such as single-cell irradiation with light ion beams. These processes, developed within the framework of the Geant4-DNA project, adopt a software design allowing their combination with other electromagnetic physics processes available in the Geant4 toolkit. This work describes the combination of Geant4-DNA electron processes with Geant4 photon processes.

30 citations