Zsolt Balogi

TL;DR: The data show that the nature of sHsp/membrane interactions depends on the lipid composition and extent of lipid unsaturation, and that sHsps can regulate membrane fluidity, and infer that the association between sHSps and membranes may constitute a general mechanism that preserves membrane integrity during thermal fluctuations.

TL;DR: Mdm1 is a novel interorganelle tethering protein that localizes to yeast ER–vacuole/lysosome junctions, and Mdm1 truncations analogous to disease-associated Snx14 alleles fail to tether the ER and vacuole and perturb sphingolipid metabolism.

TL;DR: Evidence is provided that the membrane fluidizer benzyl alcohol acts as a chaperone inducer in B16(F10) melanoma cells and it is suggested that, apart from membrane hyperfluidization in the deep hydrophobic region, a distinct reorganization of cholesterol-rich microdomains may be required for the generation and transmission of stress signals to activate hsp genes.

TL;DR: Although Hsp70 has been implicated in different steps of the metastatic process, the exact mechanisms of its action remain to be explored, and known and potential functions of HSp70 in controlling or modulating of invasion and metastasis are discussed.

TL;DR: It is suggested that the highly saturated MGlcDG functions as a "heat shock lipid" and is of potential importance in the development of acquired thermotolerance of heat/light-primed cyanobacterial thylakoids.