Damghan University

About: Damghan University is a education organization based out in Dāmghān, Iran. It is known for research contribution in the topics: Catalysis & Thin film. The organization has 971 authors who have published 2162 publications receiving 24163 citations. The organization is also known as: University of Damghan.

Progress in Conductive Polyaniline-Based Nanocomposites for Biomedical Applications: A Review.

Abstract: Inherently conducting polymers (ICPs) are a specific category of synthetic polymers with distinctive electro-optic properties, which involve conjugated chains with alternating single and double bonds. Polyaniline (PANI), as one of the most well-known ICPs, has outstanding potential applications in biomedicine because of its high electrical conductivity and biocompatibility caused by its hydrophilic nature, low-toxicity, good environmental stability, and nanostructured morphology. Some of the limitations in the use of PANI, such as its low processability and degradability, can be overcome by the preparation of its blends and nanocomposites with various (bio)polymers and nanomaterials, respectively. This review describes the state-of-the-art of biological activities and applications of conductive PANI-based nanocomposites in the biomedical fields, such as antimicrobial therapy, drug delivery, biosensors, nerve regeneration, and tissue engineering. The latest progresses in the biomedical applications of PANI-based nanocomposites are reviewed to provide a background for future research.

Advances in Antimicrobial Microneedle Patches for Combating Infections.

Abstract: Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional topical administration because of poor drug penetration across the stratum corneum This results in low bioavailability of drugs to the infection site, as well as the lack of prolonged release Emerging antimicrobial transdermal and ocular microneedle patches have become promising medical devices for the delivery of various antibacterial, antifungal, and antiviral therapeutics In the present review, skin anatomy and its barriers along with skin infection are discussed Potential strategies for designing antimicrobial microneedles and their targeted therapy are outlined Finally, biosensing microneedle patches associated with personalized drug therapy and selective toxicity toward specific microbial species are discussed