Institution
Milton Keynes Hospital
Healthcare•Milton Keynes, United Kingdom•
About: Milton Keynes Hospital is a healthcare organization based out in Milton Keynes, United Kingdom. It is known for research contribution in the topics: Population & Health care. The organization has 247 authors who have published 191 publications receiving 3953 citations.
Topics: Population, Health care, MEDLINE, Cancer, Internal medicine
Papers published on a yearly basis
Papers
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TL;DR: A randomised comparison of high-dose chemotherapy plus ABMT with the same drugs at lower doses not requiring bone-marrow rescue in patients with active Hodgkin's disease found that high doses facilitated by ABMT can lead to better disease-free survival.
973 citations
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TL;DR: An overview of the current de-escalation trials for human papillomavirus positive (HPV+) oropharyngeal carcinoma is provided and strong evidence for an improved prognosis in the viral associated cohort when treated by platinum based chemotherapy in combination with radiotherapy or primary radiotherapy is provided.
253 citations
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TL;DR: New guidelines for the management of acute mesenteric ischaemia are presented to provide recommendations for practice that will lead to improved outcomes for patients.
Abstract: Acute mesenteric ischaemia (AMI) accounts for about 1:1000 acute hospital admissions. Untreated, AMI will cause mesenteric infarction, intestinal necrosis, an overwhelming inflammatory response and death. Early intervention can halt and reverse this process leading to a full recovery, but the diagnosis of AMI is difficult and failure to recognize AMI before intestinal necrosis has developed is responsible for the high mortality of the disease. Early diagnosis and prompt treatment are the goals of modern therapy, but there are no randomized controlled trials to guide treatment and the published literature contains a high ratio of reviews to original data. Much of that data comes from case reports and often small, retrospective series with no clearly defined treatment criteria. A study group of the European Society for Trauma and Emergency Surgery (ESTES) was formed in 2013 with the aim of developing guidelines for the management of AMI. A comprehensive literature search was performed using the Medical Subject Heading (MeSH) thesaurus keywords “mesenteric ischaemia”, “bowel ischaemia” and “bowel infarction”. The bibliographies of relevant articles were screened for additional publications. After an initial systematic review of the literature by the whole group, a steering group formulated questions using a modified Delphi process. The evidence was then reviewed to answer these questions, and recommendations formulated and agreed by the whole group. The resultant recommendations are presented in this paper. The aim of these guidelines is to provide recommendations for practice that will lead to improved outcomes for patients.
220 citations
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Ryon M. Bateman1, Michael D. Sharpe1, Justin E. Jagger1, Christopher G. Ellis1 +1872 more•Institutions (226)
TL;DR: This research presents a novel probabilistic procedure called “spot-spot analysis” that allows for real-time analysis of the response of the immune system to natural disasters.
Abstract: [This corrects the article DOI: 10.1186/s13054-016-1208-6.].
180 citations
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01 Mar 2008TL;DR: Multidisciplinary research needs to investigate the models of pain and treatment in different cultural groups to allow us to understand how pain is presented and how beliefs and expectations about treatment can be married with practical solutions and effective evidence-based pain management.
Abstract: The relationship between pain and ethnicity is shaped by experience, learning and culture.Mistaken beliefs about the nature of pain and disability, resistance to treatment seeking, reluctance to comply with treatment and failure to accept responsibility of the treatment outcome are not culturally or sub-culturally specific obstacles to pain management.A cultural group's expectations and acceptance of pain as a normal part of life will determine whether pain is seen as a clinical problem that requires a clinical solution.The reviewed literature shows disparities in pain treatment based on ethnic background.Multidisciplinary research needs to investigate the models of pain and treatment in different cultural groups to allow us to understand how pain is presented and how beliefs and expectations about treatment can be married with practical solutions and effective evidence-based pain management.
146 citations
Authors
Showing all 249 results
Name | H-index | Papers | Citations |
---|---|---|---|
Paul M. Matthews | 140 | 617 | 88802 |
Mohamed H. Ahmed | 54 | 596 | 13882 |
Michele T.M. Hu | 38 | 162 | 5062 |
Benjamin Davies | 37 | 277 | 7708 |
John P. Corcoran | 19 | 91 | 1193 |
S. T. Hussain | 15 | 24 | 1279 |
Jonathan Fishman | 15 | 106 | 1040 |
Noyko Stanilov | 11 | 20 | 299 |
Mohamed H. Ahmed | 11 | 14 | 418 |
Sudipta Chattopadhyay | 10 | 28 | 658 |
John M. O’Callaghan | 9 | 34 | 639 |
Rahul Mukherjee | 9 | 45 | 534 |
Harold Ayetey | 7 | 12 | 370 |
D P Williams | 6 | 10 | 372 |
Catherine Hildyard | 6 | 11 | 159 |