Showing papers in "Health technology in 2022"

Digital technologies, healthcare and Covid-19: insights from developing and emerging nations

Abstract: COVID-19 pandemic created a global health crisis affecting every nation. The essential smart medical devices/accessories, quarantine facilities, surveillance systems, and related digital technologies are in huge demand. Healthcare, manufacturing industries, and educational institutions need technologies that allow working from a safe location. Digital technologies and Industry 4.0 tools have the potential to fulfil these customized requirements during and post COVID-19 crisis. The purpose of this research is to provide understanding to healthcare professionals, government policymakers, researchers, industry professionals, academics, and students/learners of the paradigm of different Digital technologies, Industry 4.0 tools, and their applications during the COVID-19 pandemic. Digital technologies, Industry 4.0 tools and their current and potential applications have been reviewed. The use of different Digital technologies and Industry 4.0 tools is identified. Digital technologies and Industry 4.0 tools (3D Printing, Artificial Intelligence, Cloud Computing, Autonomous Robot, Biosensor, Telemedicine service, Internet of Things (IoT), Virtual reality, and holography) offer opportunities for effective delivery of healthcare service(s), online education, and Work from Home (WFH) environment. The article emphasises the usefulness, most recent development, and implementation of Digital technologies, Industry 4.0 techniques, and tools in fighting the COVID-19 pandemic worldwide.

Semantic interoperability in health records standards: a systematic literature review

Abstract: The integration and exchange of information among health organizations and system providers are currently regarded as a challenge. Each organization usually has an internal ecosystem and a proprietary way to store electronic health records of the patient's history. Recent research explores the advantages of an integrated ecosystem by exchanging information between the different inpatient care actors. Many efforts seek quality in health care, economy, and sustainability in process management. Some examples are reducing medical errors, disease control and monitoring, individualized patient care, and avoiding duplicate and fragmented entries in the electronic medical record. Likewise, some studies showed technologies to achieve this goal effectively and efficiently, with the ability to interoperate data, allowing the interpretation and use of health information. To that end, semantic interoperability aims to share data among all the sectors in the organization, clinicians, nurses, lab, the entire hospital. Therefore, avoiding data silos and keep data regardless of vendors, to exchange the information across organizational boundaries. This study presents a comprehensive systematic literature review of semantic interoperability in electronic health records. We searched seven databases of articles published between 2010 to September 2020. We showed the most chosen scenarios, technologies, and tools employed to solve interoperability problems, and we propose a taxonomy around semantic interoperability in health records. Also, we presented the main approaches to solve the exchange problem of legacy and heterogeneous data across healthcare organizations.

Advancing the cybersecurity of the healthcare system with self-optimising and self-adaptative artificial intelligence (part 2)

Abstract: This article advances the knowledge on teaching and training new artificial intelligence algorithms, for securing, preparing, and adapting the healthcare system to cope with future pandemics. The core objective is to develop a concept healthcare system supported by autonomous artificial intelligence that can use edge health devices with real-time data. The article constructs two case scenarios for applying cybersecurity with autonomous artificial intelligence for (1) self-optimising predictive cyber risk analytics of failures in healthcare systems during a Disease X event (i.e., undefined future pandemic), and (2) self-adaptive forecasting of medical production and supply chain bottlenecks during future pandemics. To construct the two testing scenarios, the article uses the case of Covid-19 to synthesise data for the algorithms i.e., for optimising and securing digital healthcare systems in anticipation of disease X. The testing scenarios are built to tackle the logistical challenges and disruption of complex production and supply chains for vaccine distribution with optimisation algorithms.

A deep learning approach for parkinson’s disease severity assessment

Abstract: Abstract Purpose Parkinson’s Disease comes on top among neurodegenerative diseases affecting 10 million worldwide. To detect Parkinson’s Disease in a prior state, gait analysis is an effective choice. However, monitoring of Parkinson’s Disease using gait analysis is time consuming and exhaustive for patients and physicians. To assess severity of symptoms, a rating scale called Unified Parkinson's Disease Rating Scale is used. It determines mild and severe cases. Today, Parkinson’s Disease severity assessment is made in gait laboratories and by manual examination. These are time consuming and it is costly for health institutions to build and maintain laboratories. By using low-cost wearables and an effective model, aforementioned problems can be solved. Methods We provide a computerized solution for quantifiable assessment of Parkinson’s Disease symptoms severity. By using wearable sensors, our framework can predict exact symptom values to assess Parkinson’s Disease severity. We propose a deep learning approach that utilizes Ground Reaction Force sensors. From sensor signals, features are extracted and fed to a hybrid deep learning model. This model is the combination of Convolutional Neural Networks and Locally Weighted Random Forest. Results Proposed framework achieved 0.897, 3.009, 4.556 in terms of Correlation Coefficient, Mean Absolute Error and Root Mean Square Error, respectively. Proposed framework outperformed other machine and deep learning models. We also evaluated classification performance for disease detection. We outperformed most of the previous studies, achieving 99.5% accuracy, 98.7% sensitivity and 99.1% specificity. Conclusion This is the first study to use a deep learning regression approach to predict exact symptom value of Parkinson’s Disease patients. Results show that this approach can be effectively employed as a disease severity assessment tool using wearable sensors.

Machine learning models for non-invasive glucose measurement: towards diabetes management in smart healthcare

Abstract: The patients of diabetes require to observe and control their glycemic profile through continuous glucose level monitoring. The blood glucose measurement is possible through invasive, minimally invasive and non-invasive methods. Invasive method is traditional method for instant glucose measurement where glucose is measured by taking blood samples from the body. However, the repeated finger pricking increases the risk of blood-related infections and trauma. Hence, the development of non-invasive real time device is essential for smart healthcare to manage glucose-insulin balance. The paper presents machine learning models for non-invasive glucose measurement. So, various machine learning algorithms including Logistic Regression, KNN, Gaussian Naive Bayes, Linear Regression, Multi-polynomial Regression, Neural Network, XGBoost, Decision Tree, Random Forest and Support Vector Machine are applied on two dataset which are PIDD (UCI repository) and iGLU dataset (iGLU device). The comparative analysis is carried out where accuracy, training time, recall, precision, f-1 score and AUC curve is measured for classification algorithms. For regression algorithms, measures like accuracy, Mean Absolute Error (MAE) and Root Mean Square Error (RMSE) are used for comparison purpose. Random forest with 84% accuracy and 68% recall, 76% precision and 72% f1-score for PIDD and Decision tree with 70% accuracy, 8% mean absolute error (MAE) and 8.5% root mean square error (RMSE) for iGLU dataset gives best results. Clark grid analysis has also been done where all the values fall under zone A which gives 100% accuracy and the device is useful for medication purpose. The proposed work has been also compared with similar methods and the proposed work has excellent results in terms of MAD, mARD, RMSE and AvgE. The device would be ideal as non-invasive solution for continuous glucose monitoring.

An alternative approach to determination of Covid-19 personal risk index by using fuzzy logic

Abstract: COVID-19 disease is an outbreak that seriously affected the whole world, occurred in December 2019, and thus was declared a global epidemic by WHO (World Health Organization). To reduce the impact of the epidemic on humans, it is important to detect the symptoms of the disease in a timely and accurate manner. Recently, several new variants of COVID-19 have been identified in the United Kingdom (UK), South Africa, Brazil and India, and preliminary findings have been suggested that these mutations increase the transmissibility of the virus. Therefore, the aim of this study is to construct a support system based on fuzzy logic for experts to help detect of COVID-19 infection risk in a timely and accurate manner and to get a numerical output on symptoms of the virus from every person. The decision support system consists of three different sub and one main Mamdani type fuzzy inference systems (FIS). Subsystems are Common- Serious symptoms (First), Rare Symptoms (Second) and Personal Information (Third). The first FIS has five inputs, fever-time, cough-time, fatigue-time, shortness of breath and chest pain/dysfunction; the second FIS has four inputs, Loss of Taste/Smell, Body Aches, Conjuctivitis, and Nausea/Vomiting/Diarrhea; and the third FIS has three inputs, Age, Smoke, and Comorbidities. Then, we obtain personal risk index of individual by combining the outputs of these subsystems in a final FIS. The results can be used by health professionals and epidemiologists to make inferences about public health. Numerical output can also be useful for self-control of an individual.

An alternative approach to determination of Covid-19 personal risk index by using fuzzy logic

Abstract: COVID-19 disease is an outbreak that seriously affected the whole world, occurred in December 2019, and thus was declared a global epidemic by WHO (World Health Organization). To reduce the impact of the epidemic on humans, it is important to detect the symptoms of the disease in a timely and accurate manner. Recently, several new variants of COVID-19 have been identified in the United Kingdom (UK), South Africa, Brazil and India, and preliminary findings have been suggested that these mutations increase the transmissibility of the virus. Therefore, the aim of this study is to construct a support system based on fuzzy logic for experts to help detect of COVID-19 infection risk in a timely and accurate manner and to get a numerical output on symptoms of the virus from every person. The decision support system consists of three different sub and one main Mamdani type fuzzy inference systems (FIS). Subsystems are Common- Serious symptoms (First), Rare Symptoms (Second) and Personal Information (Third). The first FIS has five inputs, fever-time, cough-time, fatigue-time, shortness of breath and chest pain/dysfunction; the second FIS has four inputs, Loss of Taste/Smell, Body Aches, Conjuctivitis, and Nausea/Vomiting/Diarrhea; and the third FIS has three inputs, Age, Smoke, and Comorbidities. Then, we obtain personal risk index of individual by combining the outputs of these subsystems in a final FIS. The results can be used by health professionals and epidemiologists to make inferences about public health. Numerical output can also be useful for self-control of an individual.

Machine learning for optimizing daily COVID-19 vaccine dissemination to combat the pandemic

Abstract: Abstract Introduction Vaccines are the most important instrument for bringing the pandemic to a close and saving lives and helping to reduce the risks of infection. It is important that everyone has equal access to immunizations that are both safe and effective. There is no one who is safe until everyone gets vaccinated. COVID-19 vaccinations are a game-changer in the fight against diseases. In addition to examining attitudes toward these vaccines in Africa, Asia, Oceania, Europe, North America, and South America, the purpose of this paper is to predict the acceptability of COVID-19 vaccines and study their predictors. Materials and methods Kaggle datasets are used to estimate the prediction outcomes of the daily COVID-19 vaccination to prevent a pandemic. The Kaggle data sets are classified into training and testing datasets. The training dataset is comprised of COVID-19 daily data from the 13th of December 2020 to the 13th of June 2021, while the testing dataset is comprised of COVID-19 daily data from the 14th of June 2021 to the 14th of October 2021. For the prediction of daily COVID-19 vaccination, four well-known machine learning algorithms were described and used in this study: CUBIST, Gaussian Process (GAUSS), Elastic Net (ENET), Spikes, and Slab (SPIKES). Results Among the models considered in this paper, CUBIST has the best prediction accuracy in terms of Mean Absolute Scaled Error (MASE) of 9.7368 for Asia, 2.8901 for America, 13.2169 for Oceania, and 3.9510 for South America respectively. Conclusion This research shows that machine learning can be of great benefit for optimizing daily immunization of citizens across the globe. And if used properly, it can help decision makers and health administrators to comprehend immunization rates and create strategies to enhance them.

A systematic review of technologies and standards used in the development of rule-based clinical decision support systems

Abstract: Abstract A Clinical Decision Support System (CDSS) is a technology platform that uses medical knowledge with clinical data to provide customised advice for an individual patient's care. CDSSs use rules to encapsulate expert knowledge and rules engines to infer logic by evaluating rules according to a patient's specific information and related medical facts. However, CDSSs are by nature complex with a plethora of different technologies, standards and methods used to implement them and it can be difficult for practitioners to determine an appropriate solution for a specific scenario. This study's main goal is to provide a better understanding of different technical aspects of a CDSS, identify gaps in CDSS development and ultimately provide some guidelines to assist their translation into practice. We focus on issues related to knowledge representation including use of clinical ontologies, interoperability with EHRs, technology standards, CDSS architecture and mobile/cloud access. This study performs a systematic literature review of rule-based CDSSs that discuss the underlying technologies used and have evaluated clinical outcomes. From a search that yielded an initial set of 1731 papers, only 15 included an evaluation of clinical outcomes. This study has found that a large majority of papers did not include any form of evaluation and, for many that did include an evaluation, the methodology was not sufficiently rigorous to provide statistically significant results. From the 15 papers shortlisted, there were no RCT or quasi-experimental studies, only 6 used ontologies to represent domain knowledge, only 2 integrated with an EHR system, only 5 supported mobile use and only 3 used recognised healthcare technology standards (and all these were HL7 standards). Based on these findings, the paper provides some recommendations for future CDSS development.

A review of COVID-19’s impact on modern medical systems from a health organization management perspective

Abstract: The novel SARS-CoV-2 (COVID-19) disrupted many facets of the healthcare industry throughout the pandemic and has likely permanently altered modern healthcare delivery. It has been shown that existing healthcare infrastructure influenced national responses to COVID-19, but the current implications and resultant sequelae of the pandemic on the organizational framework of healthcare remains largely unknown. This paper aims to review how aspects of contemporary medical systems - the physical environment of care delivery, global healthcare supply chains, workforce structures, information and communication systems, scientific collaboration, as well as policy frameworks - evolved in the initial response to the COVID-19 pandemic.

Data mining in predicting liver patients using classification model

Abstract: This study proposes to identify potential liver patients based on the results of a liver function test performed during a health screening to search for signs of liver disease. It is critical to detect a liver patient at an early stage in order to treat them effectively. A liver function test's level of specific enzymes and proteins in the blood is evaluated to determine if a patient has liver disease. According to a review of the literature, general practitioners (GPs) rarely investigate any anomalies in liver function tests to the level indicated by national standards. The authors have used data pre-processing in this work. The collection has 30691 records with 11 attributes. The classification model is utilized to construct an effective prediction system to aid general practitioners in identifying a liver patient using data mining. The collected results indicate that both the Naïve Bayes and C4.5 Decision Tree models give accurate predictions. However, given the C4.5 model offers more accurate predictions than the Naïve Bayes model, it can be assumed that the C4.5 model is superior for this research. Consequently, the liver patient prediction system will be developed using the rules given by the C4.5 Decision Tree model in order to predict the patient class. The training set, suggested data mining with a classification model achieved 99.36% accuracy and on the testing set, 98.40% accuracy. On the training set, the enhanced accuracy relative to the current system was 29.5, while on the test set, it was 28.73. In compared to state-of-the-art models, the proposed approach yields satisfactory outcomes. The proposed technique offers a variety of data visualization and user interface options, and this type of platform can be used as an early diagnosis tool for liver-related disorders in the healthcare sector. This study suggests a machine learning-based technique for predicting liver disease. The framework includes a user interface via which healthcare providers can enter patient information.

Digital health RCT interventions for cardiovascular disease risk reduction: a systematic review and meta-analysis

Abstract: Heart disease is a leading cause of UK mortality. Evidence suggests digital health interventions (DHIs), such as smartphone applications, may reduce cardiovascular risk, but no recent reviews are available. This review examined the effect of DHIs on cardiovascular disease (CVD) risk scores in patients with increased CVD risk, compared to usual care alone. PubMed, Cochrane Database, Medline, and Google Scholar were searched for eligible trials published after 01/01/2010, involving populations with at least one CVD risk factor. Primary outcome was change in CVD risk score (e.g. QRISK3) between baseline and follow-up. Meta-analysis was undertaken using Revman5/STATA using random-effects modelling. Cochrane RoB-2 tool determined risk-of-bias. 6 randomised controlled trials from 36 retrieved articles (16.7%) met inclusion criteria, involving 1,157 patients treated with DHIs alongside usual care, and 1,127 patients offered usual care only (control group). Meta-analysis using random-effects model in STATA showed an inconclusive effect for DHIs as effective compared to usual care (Mean Difference, MD -0.76, 95% CI -1.72, 0.20), with moderate certainty (GRADEpro). Sensitivity analysis by DHI modality suggested automated email messaging was the most effective DHI (MD -1.09, 95% Cl -2.15, -0.03), with moderate certainty (GRADEpro). However, substantial study heterogeneity was noted in main and sensitivity analyses (I2 = 66% and 64% respectively). Quality assessment identified risk-of-bias concerns, particularly for outcome measurement. Findings suggest specific DHIs such as automated email messaging may improve CVD risk outcomes, but were inconclusive for DHIs overall. Further research into specific DHI modalities is required, with longer follow-up.The online version contains supplementary material available at 10.1007/s12553-022-00651-0.

Remanufacturing of single-use medical devices: a case study on cross-border collaboration between the UK and Nigeria

Abstract: Abstract This paper aims to evaluate the current state of the remanufacturing of medical devices, considering the differences between developed and developing countries. With reference to various socio-economic factors, the impact of remanufacturing to sustainability was evaluated and from this, single-use medical devices were deemed to be critical in minimising waste within the medical industry. This is even more critical with increasing use of single-use devices in the Coronavirus disease 2019 (COVID 19) pandemic. It was identified that cleaning is a key consideration for ensuring a safe remanufacturing process that would minimise the risk of infection to patients. Therefore, this process was evaluated and appropriate recommendations made. Although there may be some challenges, further research would be required for integration of the methodology and process outlined into the medical sector.

A herd immunity approach to the COVID-19 pandemic?

Abstract: Viral contamination is one of the most urgent and important topics of environmental pollution. COVID-19 is primarily transmitted from person to person, but can also be transmitted from person to animal. Herd immunity must meet the requirements in order to fulfill the goal of mitigating and ending COVID-19. This paper shows five reasons or conditions why herd immunity is not achieved in the present policies without proposed effective strategies in this paper. Unless one of the five reasons for the herd immunity model is met, the promise of herd immunity will not be fulfilled. Many COVID-19 policies worldwide with current vaccines do not meet the requirements. Policymakers have been relying on unreliable R. The number of daily deaths instead of the number of cases is a good indicator of the pandemic which will be mainly used in this paper. Currently, even in vaccinated countries, resurgences are being observed with new variants with spike mutations and immune escape. This paper proposes an effective multipronged approach such as a pharmacological approach and a non-pharmacological approach including digital fencing. Two tools such as scorecovid and deathdaily were used for justifying the claims. Digital fencing as well as pharmacological approaches may be able to overcome the pandemic. Two tools such as scorecovid and deathdaily showed that the proposed multipronged approach will be effective for mitigating the pandemic.

A transfer learning based deep learning model to diagnose covid-19 CT scan images

Abstract: To save the life of human beings during the pandemic conditions we need an effective automated method to deal with this situation. In pandemic conditions when the available resources becomes insufficient to handle the patient’s load, then we needed some fast and reliable method which analyse the patient medical data with high efficiency and accuracy within time limitations. In this manuscript, an effective and efficient method is proposed for exact diagnosis of the patient whether it is coronavirus disease-2019 (covid-19) positive or negative with the help of deep learning. To find the correct diagnosis with high accuracy we use pre-processed segmented images for the analysis with deep learning. In the first step the X-ray image or computed tomography (CT) of a covid-19 infected person is analysed with various schemes of image segmentation like simple thresholding at 0.3, simple thresholding at 0.6, multiple thresholding (between 26–230) and Otsu’s algorithm. On comparative analysis of all these methods, it is found that the Otsu’s algorithm is a simple and optimum scheme to improve the segmented outcome of binary image for the diagnosis point of view. Otsu’s segmentation scheme gives more precise values in comparison to other methods on the scale of various image quality parameters like accuracy, sensitivity, f-measure, precision, and specificity. For image classification here we use Resnet-50, MobileNet and VGG-16 models of deep learning which gives accuracy 70.24%, 72.95% and 83.18% respectively with non-segmented CT scan images and 75.08%, 80.12% and 99.28% respectively with Otsu’s segmented CT scan images. On a comparative study we find that the VGG-16 models with CT scan image segmented with Otsu’s segmentation gives very high accuracy of 99.28%. On the basis of the diagnosis of the patient firstly we go for an arterial blood gas (ABG) analysis and then on the behalf of this diagnosis and ABG report, the severity level of the patient can be decided and according to this severity level, proper treatment protocols can be followed immediately to save the patient's life. Compared with the existing works, our deep learning based novel method reduces the complexity, takes much less time and has a greater accuracy for exact diagnosis of coronavirus disease-2019 (covid-19).

CNN-LSTM deep learning based forecasting model for COVID-19 infection cases in Nigeria, South Africa and Botswana

Abstract: BackgroundCOVID-19 pandemic has indeed plunged the global community especially African countries into an alarming difficult situation culminating into a great deal amounts of catastrophes such as economic recession, political instability and loss of jobs. The pandemic spreads exponentially and causes loss of lives. Following the outbreak of the omicron new variant of concern, forecasting and identification of the COVID-19 infection cases is very vital for government at various levels. Hence, having knowledge of the spread at a particular point in time, swift actions can be taken by government at various levels with a view to accordingly formulate new policies and modalities towards minimizing the trajectory of the consequences of COVID-19 pandemic to both public health and economic sectors.MethodsHere, a potent combination of Convolutional Neural Network (CNN) learning algorithm along with Long Short Term Memory (LSTM) learning algorithm has been proposed in this work in order to produce a hybrid of a deep learning algorithm Convolutional Neural Network - Long Short Term Memory (CNN-LSTM) for forecasting COVID-19 infection cases particularly in Nigeria, South Africa and Botswana. Forecasting models for COVID-19 infection cases in Nigeria, South Africa and Botswana, were developed for 10 days using deep learning-based approaches namely CNN, LSTM and CNN-LSTM deep learning algorithm respectively.ResultsThe models were evaluated on the basis of four standard performance evaluation metrics which include accuracy, MSE, MAE and RMSE respectively. However, the CNN-LSTM deep learning-based forecasting model achieved the best accuracy of 98.30%, 97.60%, and 97.74% for Nigeria, South Africa and Botswana respectively; and in the same manner, achieved lesser MSE, MAE and RMSE values compared to models developed with CNN and LSTM respectively.ConclusionsTaken together, the CNN-LSTM deep learning-based forecasting model for COVID-19 infection cases in Nigeria, South Africa and Botswana dramatically surpasses the two other DL based forecasting models (CNN and LSTM) for COVID-19 infection cases in Nigeria, South Africa and Botswana in terms of not only the best accuracy of with 98.30%, 97.60%, and 97.74% but also in terms of lesser MSE, MAE and RMSE.

Medtech innovation guide: an empiric model to support medical technology innovation

Abstract: Abstract Innovation has become increasingly important for most industries to cope with rapid technological changes as well as changing societal needs. Even though there are many sectors with specific needs when it comes to supporting innovation, the medical technology sector is facing several unique challenges that both increases the lead-time from idea to finished product and decreases the number of innovations that are developed. This paper presents a proposed innovation guide that has been developed and evaluated as a support for the innovation process within medical technology research. The guide takes the unique characteristics of the medical technology sector into account and serves as a usable guide for the innovator. The complete guide contains both a structure for the process and a usable web application to support the journey from idea to finished products and services. The paper also includes a new readiness level, Sect. 4.2 to provide support both when developing and determining the readiness for clinical implementation of a medical technology innovation.

Women in Medical Physics and Biomedical Engineering: past, present and future

Abstract: Women in Medical Physics and Biomedical Engineering (WiMPBME) is a Task Group established in 2014 under the International Union of Physical and Engineering Scientists in Medicine (IUPESM). The group's main role is to identify, develop, implement, and coordinate various tasks and projects related to women's needs and roles in medical physics and biomedical engineering around the world. The current paper summarizes the past, present and future goals and activities undertaken or planned by the Task group in order to motivate, nurture and support women in medical physics and biomedical engineering throughout their professional careers. In addition, the article includes the historical pathway followed by various women's groups and subcommittees from 2004 up to the present day and depicts future aims to further these professions in a gender-balanced manner.

Biomedical/clinical engineering education and certification: fifty years of actions

Abstract: Health care is today technology driven and biomedical engineering is behind the impressive developments that reshaped medicine during the last 50 years. Biomedical Engineers (BMEs) as professionals are playing a vital role during the whole life cycle of Medical Devices (MDs), from the innovative idea to their final use and decommissioning. This rapid evolution creates a constant pressure for new knowledge and skills for the BMEs and therefore for continuous curriculum updates of education in BME, to meet current trends and market demands. Biomedical Engineering is relatively new when compared with other engineering disciplines. The earliest programs during the 1970s, most of which were at Doctoral and M.Sc. levels. B.Sc. programs were developed in most European Universities from the 1990s. Today there is an impressive trend to create new programs and the number of higher education institutions offering a BME degree is almost two hundred, just in Europe. Although biomedical engineering is playing a vital role in innovation, development, maintenance, and safe use of medical technology, BMEs are not yet recognized as a distinct professional entity and do not appear in the International Labour Organisation (ILO) lists. This is partly because biomedical engineering covers a very broad domain and includes professionals with very heterogeneous areas of specialization. Unlike in other engineering fields, where certification is a prerequisite for being a licensed professional, even for the clinical engineering, certification is not widely applied. This is mainly due to the lack of motivation since certification is not mandatory. In contrast with other health care professionals, that cannot practice their profession if they are not officially registered, such requirement does not exist for clinical engineers. In the present paper a review of the developments in BME educational programs in Europe, fifty years long, is attempted, focusing on some important initiatives and actions well known to the author. Additionally, some aspects of Clinical Engineering certification are addressed.

Machine learning approach for anxiety and sleep disorders analysis during COVID-19 lockdown

Abstract: The Severe Acute Respiratory Syndrome (SARS)-CoV-2 virus caused COVID-19 pandemic has led to various kinds of anxiety and stress in different strata and sections of the society. The aim of this study is to analyse the sleeping and anxiety disorder for a wide distribution of people of different ages and from different strata of life. The study also seeks to investigate the different symptoms and grievances that people suffer from in connection with their sleep patterns and predict the possible relationships and factors in association with outcomes related to COVID-19 pandemic induced stress and issues. A total of 740 participants (51.3% male and 48.7% female) structured with 2 sections, first with general demographic information and second with more targeted questions for each demographic were surveyed. Pittsburgh Sleep Quality Index (PSQI) and General Anxiety Disorder assessment (GAD-7) standard scales were utilized to measure the stress, sleep disorders and anxiety. Experimental results showed positive correlation between PSQI and GAD-7 scores for the participants. After adjusting for age and gender, occupation does not have an effect on sleep quality (PSQI), but it does have an effect on anxiety (GAD-7). Student community in spite of less susceptible to COVID-19 infection found to be highly prone to psychopathy mental health disturbances during the COVID-19 pandemic. The study also highlights the connectivity between lower social status and mental health issues. Random Forest model for college students indicates clearly the stress induced factors as anxiety score, worry about inability to understand concepts taught online, involvement of parents, college hours, worrying about other work load and deadlines for the young students studying in Universities.

A New method for promote the performance of deep learning paradigm in diagnosing breast cancer: improving role of fusing multiple views of thermography images

Abstract: Breast cancer is one of the deadliest cancers among women worldwide which its early detection may significantly reduce its mortality rate. Thermgraphy is a new, non-invasive, non-painful, and low-cost modality that detects abnormalities by detecting heat from the breast surface. Recent research has applied deep learning to early breast cancer diagnosis via thermography, using only the frontal view of thermograms. We combine several views of thermal images to improve the performance of pre-trained deep learning architectures in this article. This goal is achieved by combining frontal-45 data with lateral-45 and lateral45 thermograms to construct a detection model that utilizes transfer learning. Research in this area uses the Database for Mastology Research (DMR) with infrared images. In this study, transfer based deep learning methods are demonstrated to be effective in fusing several views of thermograms to diagnose breast cancer in a manner that can result in a sensitivity increase of 2-15 percent and a specificity increase of 2-30 percent compared to other deep learning-based or handcrafted schemes. Using multiple views of thermograms and transfer learning, this paper proposes a method for improving breast cancer diagnosis. Using methods based on deep learning and methods based on hand-crafted features, we evaluated the performance of the proposed model. Using the obtained results as a basis for future research, the proposed design can be improved and developed as a valid approach in interpreting breast thermography images.

Applying process mining in health technology assessment

Abstract: Propose a process mining-based method for Health Technology Assessment.Articles dealing with prior studies in Health Technology Assessment using Process Mining were identified. Five research questions were defined to investigate these studies and present important points and desirable characteristics to be addressed in a proposal. The was defined method with five steps and was submitted to a case study for evaluation.The Literature search identified six main characteristics. As a result, the five-step method proposed was applied in the radical prostatectomy surgical procedure between the robot assisted technique and laparoscopy.It was demonstrated in this article the creation of the proposal of an efficient method with its replication for other health technologies, coupled with the good interpretation of the specialists in terms of comprehensibility of the discovered patterns and their correlation with clinical protocols and guidelines.