Showing papers in "Indian Journal of Dermatology, Venereology and Leprology in 1988"

Adenoid Squamous Cell Carcinoma

Abstract: Adenoid squamous cell carcinoma occurred on the sole, an area not exposed to sunlight and devoid of pilosebaceous structure. Histopathologically, it showed atypical squamous cells, horn pearls, large alveolar spaces with papillary projections and acantholytic cells.

A Clinical and Bacteriological Study of Pyodermas.

Abstract: Three hundred and forty cases of pyoderma were studied clinically and bacteriologically. Maximum (32.35%) cases were of infectious eczematoid dermatitis, followed by secondary pyodermna (21.76%).

Prevalence of Dermatological Diseases in School Children in a Semi- Urban Area in Pondicherry.

Abstract: A total of 3835 children attending schools in the Gorimedu region of Pondicherry were examined. Prevalence rate of skin diseases was 49.1%. The most common.

Topical Human Placental Extract For the Treatment of Vitiligo.

Abstract: Fifty percent human placental hydroalcoholic extract was used topically on 34 vitiligo patients. Complete clearing of lesions was seen in 20.6% cases, whereas 50% cases showed mild to moderate improvement, and 29.4% showed no response. No serious side effects were seen in any of the patients.

Vitiligo in the Ssk Community of Bangalore (a Preliminary Report).

Abstract: Vitiligo among the community Somavashan Sahasajuna Kashatriya(SSK) of Baugalore surveyed by us during February-March, 1987, was found to be characterised by an earlier age of onset and a very high (90.38%) familial incidence. This community at present is small and is believed to have migrated'from Gujarat-Maharashtra border where the incidence of vitiligo in a related community, the Khatris is already high (3.6%). The results indicate that continuous inbreeding among the SSK community in Bangalore may have enhanced their genetic predisposition to this disease.

Occupational Dermatoses Among the Cashew Nut Workers in Karnataka.

Abstract: Seventy five female workers employed in the cashew nut industry in Karnataka to slice off the outer hard shells from the nuts and thus exposed to the chashew nut shell oil had a characteristic cauterization type of reaction manifesting as brownish-black, thickened sheets of dead skin covering the dorsal as well as the palmar aspects of hands including the fingers and feet. Smaller but similer lesions were also seen on these parts of the forearms, abdomen, neck and face which were not covered with clothes. The fingers were thinned and tapering and several nails of the hands and feet were thickened, discolored and eaten away. The other changes included loss of the dermatoglyphic patterns, maceration of the hands, small pits on the finger tips and pitted keratolysis seen in some cases only. Similar changes were also seen on the feet of both the male workers exposed to the same oil, in the section which extracts the oil from the sliced shells. In contrast 29, feamle wokers engaged to peel off the thin reddish covering on the cashew nut had normal hands and feet, except for the two callosities on the flexural aspect of the proximal phalanx of the right middle finger and proximal interphalangeal joint of the right index finger respectively, caused by the friction of the peeling knife. An open patch test with the cashew nut shell oil used as such in 17 workers produced a cauterization type of reaction in 32 workers irrespective of the nature of their duties, while the standard occluded patch test with 10% cashew nut shell oil in polyethylene glycol showed a mild cauterization type of reaction in only 6 workers. Patch tests with 1% and 0.1% concentrations of the shell oil were negative in all the workers. Two barrier creams tested to protect the workers from the cashew nut shell oil produced reasonably effective results within a week.

Multiple Keratocanthomas on the Mons Pubis and Labia Majora.

Abstract: An ederly woman developed multiple keratoacanthomas on the mons pubic and labia majora. Some lesion coalesced to from large irregular plaques with multiple craters. Biopsy of a well developed nodule revealed keratin - filled craters, pseudoepitheliomatous hyperplasia with horn pearls and dyskeratosis of prickle cells which appeared eosinophilio and glassy. Though a few lesions involuted spontaneously, some persisted. These responded well to topical 5-fluorouracil therapy. There was no recurrence of lesions, on long follow-up.

Primary Inoculation Tuberculosis.

Abstract: Primary inoculation tuberculosis in two children confined to the face was seen over a period of six months the first case was an eleven year old boy with a painless non-healing ulcerative nodule over the left ala nasi with matted' non-tender submandibular lymphadenopath-y of 2 months duration. Mantoux test and biopsies of the lesion and the lymph node helped in the diagnosis. The second child was a six-year-old boy with a painless ulcerative lesion over the left cheek of 5 weeks duration. The left submandibular group of lymph nodes were enlarged, non-tender and matted. Aspiration cytology showed eptihelioid cells, lymphocytes, polymorphs and eosinophils. Mantoux test negative initially became positive by 2 months. The lesion started subsiding with antitubercular treatment in both the cases.

Chromoblastomycosis with Squamous Cell Carcinoma.

Abstract: A 47 year old male patient had extensive verrucous lesions on the right upper limb for 33 years. One of the lesions-4eveloped ulceration which had not healed for6 years. A clinical diagnosis of chromoblastomycosis was confirmed histopathologically and mycologically, Cladosporium cladosporioides being the organism cultured. Combined treatment with amphotericin B and 5fluorouracil gave good response with most lesions resolving. A few verrucous plaques and the ulcer persisted. Biopsy from the ulcer revealed a low - grade squamous cell carcinoma which was treated with excision and grafting. A year later, the patient developed metastasis in the axillary lymph nodes which also showed fungal granuloma at the time of biopsy. The axilla was irradiated with 4500 rads and three courses of bleomycin injections were given. However, he died 10 months later following a massive bleed from an axillary vessel.

Pattern of Sexually Transmitted Diseases in and Around Udaipur.

Abstract: The patients who attended the STD clinic of our hospital during the last 10 years were studied retrospectively to work out the pattern of major sexually transmitted diseases viz. -syphilis, ionorrhoea, chancroid, lymphogranuloma vencreum and donovinosis. The total number of patients was 1093, The relative incidence of chancroid was found. higher (37.78%) than syphilis (32.47%), gonorrhoea (24 79%) mixed infections (3.38%), donovanosis (1.18%) and lymphogranuloma venereum (0.36%).

Two Cases of Cutaneous Leishmaniasis Seen in Trivandrum.

Abstract: Two cases of cutaneous leishmaniasis in Trivandrum acquired the infection while residing in Saudi Arabia. One patient responded to trivalent antimony (Fantorin) and the other to dapsone.

Sporotrichosis in north western India (Report of 5 cases).

Abstract: Five women with lympho-cutaneous sporotrichosis with a mean age of 46.8 years, were seen over the last 3 years. Four belonged to rural Himachal Pradesh and one to Saharanpur, Uttar Pradesh. Upper extremity was affected in three patients. Sporotrichum schenkie was isolated form 3 patients and confirmed by the mice pathogenicity test. S ' Schenki was demonstrated in the histopathology specimen in one patient. All the patients responded to oral potassium iodide, complete clearance occurring after a mean period of 3.5 months. One patient developed mild iodism and another had crythema nodosu'm like eurption during treatment. Himachal Pradesh seems to be harbouring pockets of sporotrichosis.

Contact Dermatitis Due to Cashew Nut (Anacardium Occidentale) Shell Oil, Pericarp and Kernel.

Abstract: A 21 year old worker developed itching, fissuring and exudative lesions on her hands and fingers, 3 year after working as a cutter in the cashew nut factory The lesions would in, prove during holidays or after she left her job Patch tests were postive with the 01% cashew nut shell oil in polyethylene glycol and also with the red pericarp covering and the kernel of cashew nuts used as such

Adenoid Cystic Carcinoma of the Skin.

Abstract: Adenoid cystic carcinoma commonly arises from the major and minor salivary glands. Primary cutaneous adenoid cystic carcinoma is extremely rare. The tumour was hard, non-tender, and fixed to the underlying stucture with visible congested veins. Histopathologically, large cell masses with adenoid or cribriform pattern, forming cystic spaces at places were seen. Solid epithelial nests and a few ductal structures were also seen. Plumonary metastases were another unusual feature in our patient perhaps not reported before.

Piedra in a North Indian Woman.

Abstract: A 28 year old north India lady had asymptomatic irregular nodules fixed on her scalp, hair for the last 15 months.' Microscopy revealed these to be piedra thoug4 the cuftwe, was negative. There was a good response to clotrimazole lotion within the first week itself.

Adenosine-deaminase (ADA) activity in Psoriasis (A Preliminary Study).

Abstract: Study of adenosine-deaminase activity 'in 23 patients hav-mg psoriasis compared with an equal number of healthy controls revealed significantly high ADA-activity in the psotiatic patients.

Mixed Form of Pemphigus Vulgaris and Dermatitls Herpetiformis.

Abstract: A 45 year old female had grouped pruritic Papules and vesicles with a few scattered tensebullae, symetrically distributed on the extensor surfaces of limbs, back and buttocks. Nikolsky's sign' was negative. Histopathology revealed intra-epidermal suprabasal cleft along with acantholysis. Eosinophilic spongiosis was also present. The patient recovered with dapsone.

Surgical Repair in Rhinophyma.

Abstract: A 55-year-old male Nepali patient developed rhinaphyma. he had rosacea aAd history of intake of alcohol for a long duration.The cosmetic defect was removed by surgical repair.

Psoriasis and Incontinentia Pigmenti Achromians

Abstract: Multiple lesions of psoriasis circumscribed to the hypopigmented patches of incontinetia pigmenti achromains were observed in a male child.

Parakeratosis Ostrcea-an Unusual Variant of Rupoid Psoriasis.

Abstract: A 25 year old male developed hard, lamellar, oyster's shell-like scaly lesions accompaniedwith psoriatic arthropathy. Occurrence of parakeratosis ostracca is rare still rare and therto unreported.

Nuts As a Cause of Contact Dermatitis of the Hands.

Abstract: To evaluate contact hypersensitivity to some of the commonly used Indian nuts, patch tests were undertaken with cashew nuts, ground nuts, almonds and pistachio in 3 groups of individuals: (1) patients exposed to the corresponding nut and having dermatitis on their fingertips, (2) controls having no dermatitis, but exposed to the nut, and (3) unexposed group. A paste prepared by Cushing the nut and used as such gave positive patch test 'reactions in, all the 6 patients tested with cashew - nut, ground - nut and almonds, and these looked to be irritant reactions. Further patch tests with these three nuts were therefore done with 1:1 dilution of the paste with distilled water. The number of patients showing positive patch tests out of the total number.

Assay of Testosterone, FSH and LH in Serum and Spermogram in Leprosy Patients.

Abstract: Testicular functions in the form of testosterone, FSH and LH levels in serum by radio-immuno-assays, complete semen examination and a few testicular biopsies were studied in 30 men with leprosy (LL-7, BL-6, BB-1, BT-12 and 'fT-4). Serum testosterone levels were lowered in all the groups. Serum FSH and LH levels were elevated in lepromatous and borderline .1epromatous leprosy. Semen analysis showed oligospermia in LL and BL groups. Lepra bacilli in smars of semen were present in 2 LL case. Leprous changes were seen in the testicular biopsies.

Flare up of Nickel Contact Dermatits Following Oral Challenge.

Abstract: A patient having contact dermatitis due to nickel on the wrist, sides of neck, thighs and legs, confirmed by patch tests with nickel sulphate, showed aggravation of the dermatitis following oral provocation with 25 mg nickel sulphate.

Necro-destructive Herpes Zoster.

Abstract: A 40 year old male patient had herpes zoster involving ophthalmic and maxillary divisions of the right trigeminal nerve which resulted in destruction of alveolar processes of bone, falling of teeth and forming of the oro-antral fistula.