Journal of Cosmetic and Laser Therapy 

About: Journal of Cosmetic and Laser Therapy is an academic journal published by Informa. The journal publishes majorly in the area(s): Laser & Intense pulsed light. It has an ISSN identifier of 1476-4172. Over the lifetime, 1062 publications have been published receiving 19641 citations.

The science of hyaluronic acid dermal fillers

Abstract: Background: The use of injectable materials for soft‐tissue augmentation has been increasing in the United States, reflecting the introduction of new hyaluronic acid (HA)‐based dermal fillers. HA d...

Cellulite treatment using a novel combination radiofrequency, infrared light, and mechanical tissue manipulation device

Abstract: Background. Most post-pubertal women exhibit cellulite, particularly in the thigh and buttock regions. The prevalence of cellulite has led to many attempts at treatment, including a variety of topical solutions, massage-based therapies, and surgical techniques—most with suboptimal clinical effects. The purpose of this controlled study was to evaluate a novel combination device involving radiofrequency, infrared light, and mechanical tissue manipulation for the treatment of cellulite. Methods. Twenty adult women (ages 25–57 years) of various skin phototypes (I–V), and with moderate bilateral thigh and buttock cellulite, received eight biweekly treatments to a randomly selected side (the contralateral side serving as a nontreated control). A combined bipolar radiofrequency, infrared light, and mechanical suction-based massage device was applied at 20 watts RF, 20 watts IR (700–1500 nm) light, and 200 millibar vacuum (750 mmHg negative pressure). Patients were evaluated using standardized digital photography and circumferential leg measurements at baseline, prior to each treatment session, and at one, three, and six months after the final treatment. Clinical improvement scores of comparable photographs using a quartile grading scale (05v25%, 1525%–50%, 2551%–75%, 35w75% improvement) were made independently by two masked medical assessors after the series of treatments. Final post-treatment body weight and patients’ subjective evaluations were recorded. Results. Ninety per cent (18/20) of patients noticed overall clinical improvement, and 17 of these 18 patients reported that they would pursue treatment of the contralateral thigh. Side effects were limited to transient erythema in most patients, and bruising was observed in 2/20 patients after the first couple of treatment sessions, but not as the treatment series progressed. Clinical improvement scores averaged 1.82 (corresponding to ,50% improvement) after the series of treatments. Circumferential thigh measurements were reduced by 0.8 cm on the treatment side. Conclusions. Cellulite can be significantly and safely reduced with the use of a noninvasive device that combines bipolar RF, infrared light, and mechanical massage. The effects of treatment appear to be prolonged, but maintenance treatments may be necessary to further enhance the clinical results achieved.

Combination of microneedle radiofrequency (RF), fractional RF skin resurfacing and multi-source non-ablative skin tightening for minimal-downtime, full-face skin rejuvenation.

Abstract: Background: In the recent years, there is a growth in demand for radiofrequency (RF)-based procedures to improve skin texture, laxity and contour. The new generation of systems allow non-invasive and fractional resurfacing treatments on one platform. Objective: The aim of this study was to evaluate the safety and efficacy of a new treatment protocol using a multisource RF, combining 3 different modalities in each patient: [1] non-ablative RF skin tightening, [2] fractional skin resurfacing, and [3] microneedling RF for non-ablative coagulation and collagen remodelling. Methods: 14 subjects were enrolled in this study using EndyMed PRO™ platform. Each patient had 8 non-ablative treatments and 4 fractional treatments (fractional skin resurfacing and Intensif). Results: The global aesthetic score was used to evaluate improvement. All patients had improvement in skin appearance. About 43% had excellent or very good improvement above 50%, 18% had good improvement between 25 and 50%, and the rest 39% had a mild...

Cellulite: a review of its physiology and treatment.

Abstract: Cellulite affects 85–98% of post‐pubertal females of all races. While not a pathologic condition, it remains an issue of cosmetic concern to a great number of individuals. Despite its high prevalence, there have been few scientific investigations into the physiology of cellulite. There have only been a few dozen peer‐reviewed articles devoted to cellulite in the medical literature in the past 30 years. There is no definitive explanation for its presentation. This greatly complicates the ability to treat or improve it. The four leading hypotheses that purport to explain the physiology of cellulite include: sexually dimorphic skin architecture, altered connective tissue septae, vascular changes and inflammatory factors. Treatment modalities can be divided into four main categories: attenuation of aggravating factors, physical and mechanical methods, pharmacological agents and laser. There are no truly effective treatments for cellulite.

Clinical, histologic and electron microscopic findings after injection of a calcium hydroxylapatite filler

Abstract: BACKGROUND: Calcium hydroxylapatite (CaHa) is one of many newly available soft tissue fillers.OBJECTIVE: We have, in this pilot study, evaluated the clinical, histologic and electron microscopic ultrastructural changes seen with CaHa at 1 and 6 months after skin injection.METHODS: Each of the three subjects was injected in the postauricular area with 0.1 cc of CaHa gel. A 3‐mm punch tissue biopsy was taken at 1 and 6 months post‐injection. Biopsies were analyzed by histopathology and electron microscopy. Clinical results after injection of the nasolabial folds were also evaluated.RESULTS: CaHa particles were found to persist at 6 months with evidence of new collagen formation being seen. Patients still showed clinical improvement at this time.CONCLUSION: This study is the first in vivo ultrastructural analysis of the biologic response to CaHa in human skin. CaHa shows clinical, histologic and electron microscopic evidence of persistence at 6 months.