Showing papers in "Journal of Laboratory and Clinical Medicine in 1982"

TL;DR: The effects of different levels of nitrogen, phosphorus, and caffeine intake on calcium balance and on certain of its components were assessed in 170 studies in normal middle-aged, but still premenopausal women.

TL;DR: The histochemical staining of aluminum provides a quick and easy method for identifying, localizing, and quantifying aluminum within the bone and may prove to be a useful tool in the study of the mechanisms of metabolic bone disease.

TL;DR: In this article, the authors described a method for the RIA of human epinephrine in unextracted plasma or serum, which is approximately 100 times more sensitive than existing in vivo bioassays for this hormone.

TL;DR: The kinetic data suggest that platelets are initially consumed, perhaps on incompletely endothelialized endovascular surfaces in the liver, and that fibrin subsequently forms secondary to local stasis, as well as that a number of different and complex processes may be ongoing in different patients.

TL;DR: The utility of the RIA is suggested in elucidating the role of hypoxia and/or insulin in increased erythropoiesis in IDM and the serum Ep titers in patients with anemias and polycythemias were compared to those of normal human subjects and agreed well with pathophysiologic mechanisms of these hemopoietic disorders.

TL;DR: As the molecular complexity or weight of a peptide increases, the mechanism for renal tubular degradation, instead of depending on luminal membrane hydrolysis, may primarily involve endocytosis and lysosomal digestion.

TL;DR: MTX appears to provide safe and effective treatment in resistive RA but requires further definitive trails and hepatotoxicity remains a serious consideration.

TL;DR: IgE and IgG antibodies against Af were measured by ELISA in sera from 15 patients with ABPA and compared with antibody levels in six patients with extrinsic asthma and immediate-type skin reactivity to Af (prick skin test 3+ or 4+) but no other evidence for ABPA.

TL;DR: The findings suggest that an appreciable fraction of severely ill, protein-malnourished patients have a reduced capacity to synthesize LEM, as judged by bioassay and an increased risk of mortality.

TL;DR: A rapid procedure for determining the percentage of oxidized alpha-1-PI in plasma or serum based on the ratio of TIC to EIC of alpha- 1- PI in these tissues, which may be useful in studies of the relationship between oxidation ofalpha-1 -PI and the development of pulmonary emphysema.

TL;DR: It is concluded that doses of Pb which produce blood [Pb] seen in many people are capable of inducing modest hypertension in male rats; higher doses fail to do so.

TL;DR: It is concluded that low serum 25-OH-D concentrations among nephrotic patients are principally the result or urinary losses of steroid.

TL;DR: The quenched-flow system has been combined with a continuous-flow modification of resistive-particle counters to follow aggregation kinetics of "single" particles, enabling derivation of apparent maximal velocities of aggregation and inducer activation constants, for characterizing platelet reactivity.

TL;DR: Increased PGE2 production, measured by radioimmunoassay in the renal cortex of rats on the HLA diet, suggested that the protective effect upon renal function in this model of chronic renal failure may be mediated by increased renal cortical PG formation.

TL;DR: The results imply that breath testing can be used to determine the capacity for intestinal sugar absorption in humans and demonstrate that prior sugar malabsorption may affect the breath H2 response to a meal.

TL;DR: The results obtained suggest that PGI2 could be present in human venous blood under physiological conditions, but only in very low concentrations.

TL;DR: The sensitivity of seven types of APBT scores to 50% reductions in the rates of aminopyrine absorption, metabolism of monomethylaminoantipyrine, intermediate carbon metabolism, and bicarbonate kinetics was evaluated with breath test curves simulated using the APBT model.

TL;DR: The findings confirm the lithogenic effect of contraceptive steroids and indicate that its causes are an increase in cholesterol secretion and a decrease in bile acid secretion.

TL;DR: Slow maturation of intestinal transport mechanisms may result in normal cycling of bile salts by 3 to 7 months of age, and accelerated hepatic bile salt synthesis rapidly increases the size of small pools at birth.

TL;DR: The findings suggest that a decrease in the availability of zinc to the fetus may represent one of the contributory factors in the growth retardation of fetal alcohol syndrome.

TL;DR: The concentration of blood kinins in normal subjects is much lower than previously reported, suggesting that kininogenases other than plasma kallikrein may generate circulating kinins.

TL;DR: COHbc is a reasonable index of VEco and consequently of the heme catabolic rate in both term and preterm infants with no clinical history of pulmonary dysfunction and inference of V Eco from COHbc may be misleading in certain cases without a consideration of the factors relating these two variables.

TL;DR: It is demonstrated that a dietary constitutent--arachidonic acid--can protect the gastric mucosa against alcohol injury by inducing the synthesis of prostaglandins by the gastrics mucosa.

TL;DR: The kinetics and the turnover and anticoagulant action in rabbits were studied of D-phenylalanyl-L-prolyl- L-arginyl-chloromethyl ketone (D-Phe-Pro-Arg-Ch/sub 2/Cl) (FPRMeCl), a synthetic irreversible inhibitor of thrombin.

TL;DR: The ANRL was derived from the renal venous effluent as the kidney exerted its nonexcretory antihypertensive function by virtue of improvement in the extraction of ANRL from fresh renal medulla and the fact that purified ANRL caused an acute vasodepressor effect (acted as a vasodilator).

TL;DR: Gentamicin insensitivity is substantial, but it is not complete, as indicated by low-grade, ongoing tubular toxicity to the organic base transport system and sensitivity to higher doses of gentamicin.

TL;DR: Aminoglycoside-resistant subpopulations of P. aeruginosa could contribute to the high number of treatment failures of Pseudomonas injections in agranulocytic patients and may account, in part, for the superiority of combined antipsuedomonal chemotherapy in this clinical situation.

TL;DR: The experience suggests that the test provides an efficient and reliable means of detecting congenital defects of galactose metabolism with a very low frequency of errors.

TL;DR: The studies reveal that the deposition of subendothelial FVIII/VWF in neointima requires the presence of endothelial cells and that relatively trivial amounts of plasmatic FV III/ VWF are deposited on neointimal connective tissue after de- endothelialization.