Journal•ISSN: 1084-8592
Molecular Diagnosis
Adis, Springer Healthcare
About: Molecular Diagnosis is an academic journal. The journal publishes majorly in the area(s): Gene & Point mutation. It has an ISSN identifier of 1084-8592. Over the lifetime, 310 publications have been published receiving 7165 citations.
Topics: Gene, Point mutation, Population, Genotype, Cancer
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TL;DR: For many years, sequencing of the 16S ribosomal RNA (rRNA) gene has served as an important tool for determining phylogenetic relationships between bacteria as discussed by the authors, and the features of this molecular target that make it a useful phylogenetic tool also make it useful for bacterial detection and identification in the clinical laboratory.
345 citations
TL;DR: Aptamers are single-stranded oligonucleotides derived from an in vitro evolution protocol called systematic evolution of ligands by exponential enrichment (SELEX) adapted to the use of 5-bromo and 5-iodo deoxyuridine residues that can be specifically cross-linked to proteins.
216 citations
TL;DR: Data show that acatalasemia may be a syndrome with clinical, biochemical, genetic characteristics rather than just a simple enzyme deficiency.
195 citations
TL;DR: A novel method for DNA extraction from specimens containing spores and oocysts of Enterocytozoon bieneusi and Cryptosporidium parvum, respectively is described and it is estimated that this method may increase the sensitivity of parasite DNA detection in fecal specimens up to tenfold.
184 citations
TL;DR: The Invader technology, developed for the detection of nucleic acids, is a signal amplification system able to accurately quantify DNA and RNA targets with high sensitivity and incorporates a homogeneous fluorescence readout.
179 citations