Neurodegeneration 

TL;DR: The most likely explanation is that inclusions and other visible protein aggregates represent an end stage of a molecular cascade of several steps, and that earlier steps in the cascade may be more directly tied to pathogenesis than the inclusions themselves as discussed by the authors.

TL;DR: This study demonstrates that the MPTP mouse model replicates several key features of neurodegeneration of DA neurons in PD and provides no in vivo evidence that, using this specific paradigm of injection, MPTP kills DA neurons by apoptosis.

TL;DR: This paper reviewed recent progress in understanding of the evolution of early AD with particular reference to the symptomatic pre-dementia stage designated "mild cognitive impairment", emphasizing work on the early cognitive profile and associated neuroimaging studies.

TL;DR: Dementia results from a combination of structural and neurochemical pathologies and the most reliable index of cognition in both postmortem and biopsy brain is synapse loss.

TL;DR: The results suggest that microglial activation may be involved in the sequence of pathological changes that lead to dopaminergic neuronal damage after MPTP intoxication.