Showing papers in "Progress in Cardiovascular Diseases in 2013"

TL;DR: Gaining a more thorough understanding of the links between MDD and heart disease, and how best to diagnose and treat depression among these patients, has the potential to substantially reduce morbidity and mortality from CVD.

TL;DR: Future randomized trials using HR variability/turbulence as one of the pre-defined inclusion criteria will show whether routine measurement of HR variability andurbulence will become a routine clinical tool for risk stratification of cardiac patients.

TL;DR: The leading CVD cause of death and disability in 2010 in sub-Saharan Africa was stroke; the largest relative increases in CVD burden between 1990 and 2010 were in atrial fibrillation and peripheral arterial disease.

TL;DR: The goal of this report is to provide a review of the current understanding of adherence to cardiovascular medications from the point of view of prescribing clinicians and cardiovascular researchers.

TL;DR: There are few sustained telemedicine services in Africa with the exception of tele-education, and there is an expectation that mobile phones will facilitate a range of teleMedicine activities in Africa.

TL;DR: The evidence for a link between PTSD and CVD is reviewed and potential mechanisms for that association are discussed, as well as future directions for research are discussed.

TL;DR: The role of anxiety in the development of CVD and its potential as a key target for primordial prevention strategies are considered, as well as mechanisms by which anxiety may influence CVD.

TL;DR: Quality-of-life studies consistently show that functional impairment in persons with recurrent syncope is similar to other chronic diseases, and in older adultssyncope is a major cause of morbidity and mortality with enormous personal and wider health economic costs.

TL;DR: A review of recent developments in the field of "patch" devices primarily designed for very long-term monitoring of cardiac arrhythmic events that hold promise for a variety of cardiac monitoring applications.

TL;DR: It is demonstrated that the cost of care for major CVDs and diabetes is beyond the coping capacities of individuals, households, families and governments in most African countries.

TL;DR: Targeted research into modifying the upstream regulation or downstream effects of the TGF-β1 pathway may provide opportunities for intervention to attenuate TAA progression.

TL;DR: Consistent associations have been seen for general psychological stress, work-related stress, locus of control and depression with CVD risk, despite the strength of this association the results from behavioural and pharmacological interventions have not clearly resulted in improved outcomes.

TL;DR: Evidence in behavioral epidemiology, stress and biological processes with implications for cardiopathogenesis, and clinical and pharmacologic treatment of anger/hostility has the potential to reduce anger and its health-damaging effects are reviewed.

TL;DR: There is a need for parameters and markers besides aortic aneurysm size for use in diagnosing and monitoring TAAs so as to prevent natural complications of this disease.

TL;DR: Improved diagnostic and treatment algorithms are urgently needed to improve patient quality-of-life, reduce health service use, and lower costs related to the evaluation of syncope.

TL;DR: The research on psychological distress including anger, depression and anxiety on cardiac arrhythmias, insights into proposed mechanisms, and potential avenues for future research are reviewed.

TL;DR: For these rare conditions, both open and endovascular therapy will continue to work in harmony to enhance and extend the capabilities of modern surgical management.

TL;DR: This work discusses popliteal, femoral, carotid, subclavian, upper limb, visceral and false aneurysms, focussing on the risk of rupture and thromboembolism, and current thresholds for intervention, based on the available published literature.

TL;DR: The literature on different therapy choices for vasovagal syncope and neurogenic orthostatic hypotension is reviewed to give recommendations on tailored approaches to the treatment of these conditions.

TL;DR: Rising body mass index, especially in women in Southern Africa; and rising systolic blood pressure in East Africa for both sexes, and in West Africa for women are the major cardiometabolic risk factors.

TL;DR: Electrophysiologic and ionic mechanisms underlying TWA's predictivity, principles and practical aspects of AECG-based TWA monitoring, clinical evidence supporting this approach to SCD risk stratification, and current and potential applications in guiding medical therapy are addressed.

TL;DR: Globalization processes, the food environment, and dietary health outcomes in SSA are explored through the use of trend analyses and structural equation modelling and the findings are considered in the context of global barriers and facilitators for healthy public policy.

TL;DR: Data show that there are shared genetic factors that may give rise to both depression and CVD, and these genetic risks appear to be modified by gender, and this pleiotropic effect suggests that a single pathway, when perturbed, gives rise to the dual phenotypes of CVD and depression.

TL;DR: This review aims to provide a comprehensive overview of invasive and non-invasive ECG monitoring strategies in patients with atrial fibrillation, with a special focus on the diagnosis of atrialFibre, and on follow-up of patients after catheter ablation for atrial Fibrillation ablation.

TL;DR: Holter monitoring can be used for risk stratification of patients, in the context of the prognostic value of non-sustained ventricular arrhythmias in various clinical settings, as discussed in detail.

TL;DR: The current state-of-the-art knowledge regarding clinical significance of HRT in detection of autonomic dysfunction and regarding the prognostic significance of this parameter in predicting all-cause mortality and sudden death are focused on.

TL;DR: The QT Variability Index is a non-invasive measure of repolarization lability that has been applied to a wide variety of subjects with cardiovascular disease and is a ratio of normalized QT variability to normalized heart rate variability, and therefore includes an assessment of autonomic nervous system tone.

TL;DR: The definition of syncope has clinical and pathophysiological parts as mentioned in this paper, and the signs and symptoms of synope rely on three steps, starting with the cause of symptoms and including the response of the systemic circulation and neurological effects.

TL;DR: This chapter will provide a practical look at the rapidly evolving field regarding the genetics of thoracic aortic aneurysm with a discussion of the molecular genetics at the RNA level, including a promising investigational "RNA Signature" test that has been developing at Yale.

TL;DR: The emergence of the mobile smartphone coupled with this digital capacity is leading to the recent development of Holter smartphone applications and the potential of point-of-care applications utilizing the Holter smartphones and a vast array of new non-invasive sensors is evident in the not too distant future.