Showing papers in "Synthesis in 1974"
232 citations
91 citations
TL;DR: Cyclopentadien (I) and Cyclohexadien(IV) werden beim bestrahlen mit einer Quecksilberhochdrucklampe (Pyrexfilter) unter einer Sauerstoffatmosphare in Methanol in Gegenwart eines Photosensibilisators and danach with Thioharnstoff als Reduktionsmittel zu cis-2-Cyclopsenten-1,4-diol (II) bzw.
Abstract: Cyclopentadien (I) und Cyclohexadien (IV) werden beim Bestrahlen mit einer Quecksilberhochdrucklampe (Pyrexfilter) unter einer Sauerstoffatmosphare in Methanol in Gegenwart eines Photosensibilisators und danach mit Thioharnstoff als Reduktionsmittel zu cis-2-Cyclopenten-1,4-diol (II) bzw. cis-2-Cyclohexen-1,4-diol (V) umgesetzt.
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TL;DR: Pyrrolopyrimidine ring systems have been extensively studied in the literature as discussed by the authors, where the five main structural forms are discussed individually together with accounts of the syntheses, reactions, and transformations of some examples.
Abstract: This review covers various synthetic approaches to the pyrrolopyrimidine ring systems. The five main structural forms are discussed individually together with accounts of the syntheses, reactions, and transformations of some examples. A short account of the importance of these systems in pharmacology, biochemistry, chemistry, and industry is also given. 1. Scope 2. Pyrrolo[3,2-d]pyrimidines 2.1. Synthesis from Pyrimidine Derivatives 2.2. Transformations 3. Pyrrolo[3,4-d]pyrimidines 3.1. Synthesis from Pyrrole Derivatives 3.2. Synthesis from Pyrimidine Derivatives 3.3. Transformations 4. Pyrrolo[2,3-d]pyrimidines 4.1. Synthesis from Pyrimidine Derivatives 4.2. Synthesis from Pyrrole Derivatives 4.3. Transformations 5. Pyrrolo[1,2-a]pyrimidines 5.1. Synthesis from Pyrrole Derivatives 5.2. Synthesis from Open Chain Intermediates 5.3. Synthesis from Pyrimidine Derivatives 5.4. Synthesis from a Lactam 5.5. Transformations 6. Pyrrolo[1,2-c]pyrimidines 6.1. Synthesis from Pyrrole Derivatives 6.2. Synthesis from Pyrimidine Derivatives 6.3. Chemical Properties and Reactions 7. Applications 8. Addendum
TL;DR: In this paper, the electrophile in the latter case could also be an alkyl halide, oxirane, carbonyl compd., nitrile, or CO2.
Abstract: H2C:CHCH2OR (R = tetrahydropyranyl) gave a mixt. of H2C:CHCHR1OH and R1CHCH2CHO after metalation and reaction with an electrophilic agent R1X, whereas metalation of MeCH:CHOR (R = tetrahydropyranyl) with EtCHMeLi, followed by reaction with MeI and acid hydrolysis gave EtCOMe. The electrophile in the latter case could also be an alkyl halide, oxirane, carbonyl compd., nitrile, or CO2. [on SciFinder (R)]