Showing papers in "Synthetic Communications in 2000"

TL;DR: Anhydrous indium trichloride (InCl3) was found to catalyze the electrophilic substitution reaction of indole with aromatic aldehydes and Schiff's bases which resulted in an efficient synthesis of bis-indolylmethanes in good to excellent yield as mentioned in this paper.

TL;DR: Trifluoromethylsulfenylation of masked carbonyl functions, such as the enamines using N-(trifluorsophylthio)phthalimide is described in this article.

TL;DR: In this article, the coupling reaction of diverse arylhalogenids with phenyl-boronic acid under solvent-free conditions has been performed using a palladium catalyst.

TL;DR: Diacylhydrazines undergo cyclization upon treatment with triflic anhydride and pyridine to form the corresponding 1,3,4-oxadiazoles in yields ranging from 70-95%.

TL;DR: In this article, the synthesis and characterisation of new 1,5-benzodiazepines prepared from 4,6-diacetylresorcinol is reported. But this work is restricted to a single class of drugs.

TL;DR: Ammonium acetate and basic alumina catalyzed efficiently the Knoevenagel condensation of aldehydes and ketones with active methylene compounds under solvent-free condition where olefinic products were obtained in high yields.

TL;DR: In this paper, the initial formation of deoxybenzoin 3 from phenyl acetic acid 1 and phenol 2 in the presence of BF3.Et2O followed by its treatment at room temperature with N, N'-dimethyl (chloromethylene) ammonium chloride, generated by reacting PCl5 with DMF provides a mild and efficient route for a "one pot" synthesis of Isoflavones in high yields.

TL;DR: Magnesium bromide is an efficient catalyst for the acetylation and benzoylation of a variety of primary and secondary alcohols with the respective acid anhydrides at ambient temperature.

TL;DR: In this article, a regio-and stereoselective manner with alcohols, acetic acid and water in the presence of catalytic amounts of bismuth(III) chloride, affording β-alkoxy and β-acetoxy alcohols and diols in high yields.

TL;DR: In this paper, the Biginelli compounds were synthesized in a one-pot reaction between β-keto esters, aryl aldehydes, and urea.

TL;DR: Aqueous trimethylamine mediated Baylis-Hillman coupling of alkyl acrylates with aldehydes was described in this article, where the coupling was shown to be a Baylis and Hillman coupling.

TL;DR: In this paper, several benzaldehydes were condensed with barbituric acid under infrared irradiation, in absence of solvent, affording the corresponding 5-benzylidene barbiturate acids.

TL;DR: In this article, a convenient and efficient one pot sequence was developed for the transformation of alcohols to amines using Sodium azide, triphenylphosphine in CC14-DMF.

TL;DR: A combination of oxalic acid dihydrate and sodium nitrite in the presence of wet SiO2 was used as an effective oxidizing agent for the oxidation of dihydropyridines to their corresponding pyridine derivatives at room temperature with excellent yields as discussed by the authors.

TL;DR: A solid state method for the oxidation of thiols using benign oxidant, ammonium persulfate, was described in this paper, where the method was shown to work well in the presence of a small amount of noise.

TL;DR: Alcohols and Phenols are protected efficiently with dihydropyran(DHP) in the presence of catalytic amounts of zirconium tetrachloride in dichloromethane.

TL;DR: In this article, the Dess-Martin periodinane was used to generate cycloadducts for hydroxamic acids, N-hydroxyureas, and Nhydroxy carbamates.

TL;DR: In this paper, the condensation of aromatic aldehyde with isopropylidene malonate or 5,5-dimethyl-1,3-cyclohexanedione is carried out in DMF as solvent without catalyst.

TL;DR: In this article, a combination of NaHSO4 and NaNO2 was used as an effective oxidizing agent for the oxidation of dihydropyridines to their corresponding pyridine derivatives at room temperature.

TL;DR: In this article, a method for the transformation of aromatic, hetero-aromatic and aliphatic aldehydes into carboxylic acids is presented based on THF using 30% hydrogen peroxide in the presence of 5 molar % of selenium(IV) oxide.

TL;DR: In this paper, the authors used formic acid and raney nickel to selectively reduce aliphatic and aromatic nitro compounds to their corresponding amino derivatives in good yields using a system compatible with several sensitive functionalities.

TL;DR: In this article, an efficient method for secondary amides by reaction of alcohols with nitriles was described using a catalytic amount of Fe3+-montmorillonite K10.

TL;DR: In this article, a ring opening reaction of epoxides is achieved by aliphatic alcohols and water in the presence of catalytic amounts of ferric perchlorate.

TL;DR: Bismuth(III) acetate catalyzes the synthesis of azlactones from aromatic aldehydes in moderate to good yields via the Erlenmeyer synthesis as mentioned in this paper.

TL;DR: In this article, aromatic nitro compounds were reduced to respective amines in high yields by using 5% platinum on carbon with ammonium formate or formic acid as hydrogen donor.

TL;DR: In this paper, direct mono or dinitration of phenol was also performed with 2H2O, metal nitrates (ionic) and wet SiO2 under different reaction conditions.

TL;DR: In this article, a combination of inorganic acidic salts and sodium nitrite in dichloromethane at room temperature is used to convert thiols to their corresponding thionitrite.

TL;DR: A combination of inorganic acidic salts or silica gel supported inorganic acids and sodium nitrite in the presence of wet SiO2 was used as an effective nitrosating agent for the nitrosation of secondary amines to their corresponding nitroso drivatives under mild and heterogeneous conditions in moderate to excellent yields as discussed by the authors.

TL;DR: In this paper, the active catalyst was shown to be RuO4 and the biphasic H2O -CCl4-CH3CN media was used for the same purpose.

TL;DR: In this paper, a simple one pot procedure for the synthesis of N,N'-unsymmetrical ureas using phenyl chloroformate in THF was described, and the synthesis was shown to work well in a variety of applications.