Showing papers in "Trends in Cardiovascular Medicine in 2022"

TL;DR: The CardioVerse represents a theoretical term for the embracement of the metaverse by cardiovascular medicine, encompassing the endless possibilities as well as the challenges that it holds and introduces new dimensions to disease education, prevention and diagnosis as mentioned in this paper .

TL;DR: The ongoing COVID-19 pandemic highlighted a significant interplay between cardiovascular disease (CVD), COVID19 related inflammatory status, and depression as mentioned in this paper , which is a non-negligible risk factor for CVD as well as a variety of mental health issues, and in particular, depression.

TL;DR: It is hypothesized that a dual approach may be of value because I/R injury patients are predestined with multiple comorbidities and systemic low-grade inflammation, which requires targeted intervention before other strategies can be fully effective.

TL;DR: In this paper , the effects of habitual coffee and tea consumption on cardiovascular disease (CVD) prevention were investigated. But, the authors did not consider the effect of green tea consumption.

TL;DR: In this paper , the authors investigated the role of platelets in the pathogenesis of vaccine-induced immune thrombotic Thrombocytopenia in COVID-19-associated coagulopathy.

TL;DR: In this article , the authors summarize the body of evidence implicating each of these risk factors in residual coronary heart disease risk, including systemic inflammation, diabetes mellitus, high-density lipoprotein, plasma triglycerides (TG), residual lipoproteins (RLP), and vascular endothelial dysfunction (ED).

TL;DR: In this article , the authors used an enzyme-linked immunosorbent assay (ELISA) to detect thrombocytopenia and thromboembolism after COVID-19 vaccination.

TL;DR: In this article , the role of LPS in the initiation and progression of atherosclerotic lesion development was investigated, and the major cell receptors on inflammatory cells, like macrophages, monocytes, and dendritic cells (DCs), were identified as the major sources of vascular inflammation during atherosclerosis.

TL;DR: In this article , a review aims to expound on the mechanism whereby flow shear stress promotes vasodilation through the proposed mechanosensitive GPCRs in ECs, including G protein-coupled receptor 68, histamine H1 receptors, sphingosine-1-phosphate receptor 1, and bradykinin B2 receptors.

TL;DR: In this article , the authors describe the current state of knowledge on aortic dissection and discuss any controversies surrounding it, and discuss treatment improvements in dissection treatment options, i.e., the frozen elephant trunk approach, thoracic endovascular repair, and the endo-Bentall concept as a future option.

TL;DR: In this article , a meta-analysis aimed to identify the most frequent causes of sudden cardiac death in individuals aged ≤35 years, the differences between athletes and non-athletes and geographic areas.

TL;DR: In this article , the authors reviewed the diagnostic approach to patients with suspected coronary microvascular dysfunction as a cause of ischemic syndromes and also suggested a classification of chronic and acute micro-vascular coronary ischemia, including myocardial infarction with normal coronary arteries.

TL;DR: In this paper , the authors discuss the pro-atherosclerotic implication of this phenomenon that inevitably occurs in the context of a more complex regulation mediated by IFN-γ, and discuss an emerging therapeutic option for patients with progressive atherosclerosis.

TL;DR: In this article , the authors proposed a tailored protocol in which specific targeting of the atrial myocardium is achieved while sparing adjacent tissues is theoretically feasible, increasing the safety of the procedure.

TL;DR: This paper performed a systematic review with meta-analysis with reconstructed time-to-event data of studies published by January 2022 to compare late outcomes of patients with bicuspid aortic valve (BAV) stenosis versus TAV patients who underwent TAVI.

TL;DR: Stereotactic ablative radiotherapy (SABR) has been widely used in the treatment of ventricular tachycardia (VT) but may also have potential in other arrhythmias as well, often termed stereotactic arrhythmia radiotherapy as mentioned in this paper .

TL;DR: The antiarrhythmic mechanisms involved include reverse atrial and ventricular remodeling, amelioration of mitochondrial function, reduction of hypoglycemic episodes with their attendant arrhythmogenic effects, attenuated sympathetic nervous system activity, regulation of sodium and calcium homeostasis, and suppression of prolonged ventricular repolarization as discussed by the authors .

TL;DR: In this paper , the authors provide healthcare providers working in the field of cardiovascular medicine with an overview of AI and machine learning (ML) algorithms that have passed the initial tests and made it into contemporary clinical practice.

TL;DR: In this paper , the authors present a review of the current literature on the association between acute myocardial infarction and mental health in women, including the impact on morbidity, mortality, and quality of life.

TL;DR: In this paper , the role of microRNAs in the regulation of biological processes by interfering in gene expression at the post-transcriptional level was uncovered, which may provide novel opportunities for RNA-based therapeutic interventions to address the increased risk of myocardial infarction (MI) in diabetes.

TL;DR: An overview of common neurologic manifestations of COVID-19 is presented, in particular focusing on the cerebrovascular complications, and proposed pathophysiology, and growing evidence also suggests during a chronic phase, the post-acute sequalae of CO VID-19 (PASC).

TL;DR: In this paper , it was shown that a single spot PAC is a deeply flawed index of true aldosterone status, so that many referred patients with PA fall at the first hurdle.

TL;DR: In this paper , the authors describe the extensive cardioneural network that encompasses the heart, brain, spinal cord, and ganglia throughout the body, and then discuss ambulatory and laboratory-based non-invasive measures of this network that both measure psychological stress and heart disease severity.

TL;DR: In this paper , the authors survey the literature implicating myocyte enhancer factor 2 (Mef2) in hypertension induced cardiac hypertrophy, towards illuminating points of interest for understanding and potentially treating heart failure.

TL;DR: The NET-Heart project as mentioned in this paper is an initiative to systematically review all these devastating endemic conditions affecting the heart to spread knowledge and propose algorithms for early diagnosis and treatment of Zika's cardiovascular complications.

TL;DR: In this paper , the authors highlight important challenges and considerations when providing genetics consults and testing in pediatric CHD and illustrate the role of a dedicated CHD genetics clinic, highlighting that a genetic diagnosis can have clinical utility that justifies testing early in life, adequate genetic counselling is crucial to ensure families are supported, understand the range of possible results, and are prepared for new or unexpected health information.

TL;DR: In this article , the most common conditions associated with SCAD, including predisposing factors and triggers, and potential mechanisms leading to SCAD development are discussed. And the main genetic research findings that have shed further light on SCAD pathophysiology are reported.

TL;DR: In this paper , the authors summarized the various sources of PM2.5, its components, and the concentrations of ambient PM 2.5 in various settings, and discussed the experimental findings to date that evaluate the potential adverse effects on cardiovascular homeostasis and function.

TL;DR: In this paper , it was shown that reduction in heart rate via vagal activation and/or sympathetic inhibition is propitious to improve outcomes in patients with various medical conditions, including cancer.

TL;DR: In this article , the authors discuss a plethora of issues when researching ablation techniques, from control arm ablation strategy to the relevance of outcome measures, and discuss these issues in the context of the current evidence base.