Journal ArticleDOI
1,3-Diindolylureas and 1,3-Diindolylthioureas: Anion Complexation Studies in Solution and the Solid State
Reads0
Chats0
TLDR
These easy-to-make compounds adopt relatively planar conformations in the solid-state and are able to donate four hydrogen bonds and yet not fill the coordination sphere of carbonate or phosphate, allowing two or three receptors to bind to each anion in theSolid-state.Abstract:
1,3-Diindolylureas and thioureas have been synthesised and their anion complexation properties in solution studied. Whilst diindolylthioureas showed only moderate afinities and selectivities, diindolyureas show remarkably high affinity for dihydrogen phosphate in solution for an acyclic, neural receptor in water/[D-6]DMSO mixtures. These easy-to-make compounds adopt relatively planar conformations in the solid-state and are able to donate four hydrogen bonds and yet not fill the coordination sphere of carbonate or phosphate, allowing two or three receptors to bind to each anion in the solid-state.read more
Citations
More filters
Journal ArticleDOI
(Thio)urea organocatalysis—What can be learnt from anion recognition?
Zhiguo Zhang,Peter R. Schreiner +1 more
TL;DR: The present critical review outlines the close relationship and mutual interplay between molecular recognition, active site considerations in enzyme catalysis involving anions, and organocatalysis utilizing explicit hydrogen bonding.
Journal ArticleDOI
Anion recognition by hydrogen bonding: urea-based receptors.
TL;DR: It will be shown that the efficiency of urea as a receptor subunit depends on the presence of two proximate polarised N-H fragments, capable of chelating a spherical anion or of donating two parallel H-bonds to the oxygen atoms of a carboxylate or of an inorganic oxoanion.
Journal ArticleDOI
Artificial receptors for the recognition of phosphorylated molecules
Amanda E. Hargrove,Sonia Nieto,Tianzhi Zhang,Jonathan L. Sessler,Jonathan L. Sessler,Eric V. Anslyn +5 more
TL;DR: Artificial Receptors for the Recognition of Phosphorylated Molecules and their applications in drug discovery and personalized medicine are described.
Journal ArticleDOI
Anion complexation and sensing using modified urea and thiourea-based receptors
TL;DR: This critical review highlights recent advances in the structurally modified (thio)urea-based receptors for anion complexation and sensing.
Journal ArticleDOI
Anion receptor chemistry: highlights from 2008 and 2009
TL;DR: This critical review covers advances in anion complexation in the year 2008 and 2009 by discussing anion receptors that employ hydrogen bond donors, electrostatic interactions, Lewis acidic centres and combinations of these three types of binding interaction to complex anions.
References
More filters
Book ChapterDOI
Processing of X-ray diffraction data collected in oscillation mode
Zbyszek Otwinowski,Wladek Minor +1 more
TL;DR: The methods presented in the chapter have been applied to solve a large variety of problems, from inorganic molecules with 5 A unit cell to rotavirus of 700 A diameters crystallized in 700 × 1000 × 1400 A cell.
Journal ArticleDOI
Anion Recognition and Sensing: The State of the Art and Future Perspectives
Paul D. Beer,Philip A. Gale +1 more
TL;DR: Anion recognition chemistry has grown from its beginnings with positively charged ammonium cryptand receptors for halide binding to a plethora of charged and neutral, cyclic and acyclic, inorganic and organic supramolecular host systems for the selective complexation, detection, and separation of anionic guest species.
Journal ArticleDOI
Artificial Organic Host Molecules for Anions
Journal ArticleDOI
EQNMR : a computer program for the calculation of stability constants from nuclear magnetic resonance chemical shift data
TL;DR: In this article, a computer program has been elaborated which uses the complexation-induced displacements of NMR chemical shifts to calculate the stability constants for the general reaction (i) which gives the generalised stability constant (ii).
Journal ArticleDOI
Nature of Urea−Fluoride Interaction: Incipient and Definitive Proton Transfer
Massimo Boiocchi,Laura Del Boca,David Esteban Gómez,Luigi Fabbrizzi,Maurizio Licchelli,Enrico Monzani +5 more
TL;DR: The orange-red deprotonated urea solution uptakes carbon dioxide from air to give the tetrabutylammonium salt of the hydrogencarbonate H-bond complex, [Bu4N][1.HCO3], whose crystal and molecular structures have been determined.