A Longitudinal Investigation of Mortality in Anorexia Nervosa and Bulimia Nervosa
Debra L. Franko,Aparna Keshaviah,Kamryn T. Eddy,Meera Krishna,Martha C. Davis,Pamela K. Keel,David B. Herzog +6 more
Reads0
Chats0
TLDR
It is suggested that a long duration of illness, substance abuse, low weight, and poor psychosocial functioning raise the risk for mortality in anorexia nervosa.Abstract:
ObjectiveAlthough anorexia nervosa has a high mortality rate, our understanding of the timing and predictors of mortality in eating disorders is limited. The authors investigated mortality in a long-term study of patients with eating disorders.MethodBeginning in 1987, 246 treatment-seeking female patients with anorexia nervosa or bulimia nervosa were interviewed every 6 months for a median of 9.5 years to obtain weekly ratings of eating disorder symptoms, comorbidity, treatment participation, and psychosocial functioning. From January 2007 to December 2010 (median follow-up of 20 years), vital status was ascertained with a National Death Index search.ResultsSixteen deaths (6.5%) were recorded (lifetime anorexia nervosa, N=14; bulimia nervosa with no history of anorexia nervosa, N=2). The standardized mortality ratio was 4.37 (95% CI=2.4–7.3) for lifetime anorexia nervosa and 2.33 (95% CI=0.3–8.4) for bulimia nervosa with no history of anorexia nervosa. Risk of premature death among patients with lifetime ...read more
Citations
More filters
Journal ArticleDOI
What can we learn about eating disorder mortality from eating disorder diagnoses at initial assessment? A Danish nationwide register follow-up study using record linkage, encompassing 45 years (1970-2014).
TL;DR: In this paper, a registry-based observational epidemiological study was conducted to study the mortality outcome for eating disorder patients in both boys and men, and the results showed that ED-diagnosis increased the risk of premature mortality for both genders.
Journal ArticleDOI
Are poor set-shifting and central coherence associated with everyday function in anorexia nervosa? A systematic review.
TL;DR: A systematic electronic database search yielded 13 studies which included participants with current or lifetime Anorexia Nervosa where scores on a neuropsychological test of set-shifting or central coherence were directly or indirectly compared to a functional outcome measure as discussed by the authors.
Journal ArticleDOI
Functional hypothalamic amenorrhoea — diagnostic challenges, monitoring, and treatment.
Elżbieta Sowińska-Przepiera,Elzbieta Andrysiak-Mamos,Grażyna Jarząbek-Bielecka,Aleksandra Walkowiak,Lilianna Osowicz-Korolonek,Małgorzata Syrenicz,Witold Kędzia,Anhelli Syrenicz +7 more
TL;DR: Treatment of chronic anovulation, menstrual disorders, and secondary amenorrhea resulting from hypothalamic disorders should be aimed at the elimination of the primary cause, i.e. a decrease in psycho-emotional strain, avoidance of chronic stressors, reduction of physical exercise level, or optimisation of BMI in patients who lose weight.
Journal ArticleDOI
A comparison of the metabolic complications and hospital course of severe anorexia nervosa by binge-purge and restricting subtypes
TL;DR: Understanding the pathophysiologic differences between severe AN-R and AN-BP is essential to understanding the abnormalities seen on clinical presentation, guiding appropriate clinical treatment, and predicting medical complications during refeeding.
Journal ArticleDOI
Diagnosis and Evaluation of Eating Disorders in the Pediatric Patient.
Briana Sacco,Urszula B Kelley +1 more
TL;DR: The current diagnostic criteria for pica, rumination disorder, anorexia nervosa, bulimia nervosi, avoidant restrictive food intake disorder, binge-eating disorder, other specified feeding or eating disorder, and unspecified feeding oreating disorder as described in The Diagnostic and Statistical Manual of Mental Disorders, fifth edition are provided.
References
More filters
Journal ArticleDOI
Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders: A Meta-analysis of 36 Studies
TL;DR: In this article, a systematic literature search, appraisal, and meta-analysis were conducted of the MEDLINE/PubMed, PsycINFO, and Embase databases and 4 full-text collections (ie, ScienceDirect, Ingenta Select, Ovid, and Wiley-Blackwell Interscience).
Journal ArticleDOI
The Longitudinal Interval Follow-up Evaluation. A comprehensive method for assessing outcome in prospective longitudinal studies
Martin B. Keller,Philip W. Lavori,Barbara Friedman,Eileen Nielsen,Jean Endicott,Pat McDonald-Scott,Nancy C. Andreasen +6 more
TL;DR: The Longitudinal Interval Follow-up Evaluation (LIFE) is an integrated system for assessing the longitudinal course of psychiatric disorders that consists of a semistructured interview, an Instruction booklet, a coding sheet, and a set of training materials.
Journal ArticleDOI
Epidemiology of Eating Disorders: Incidence, Prevalence and Mortality Rates
TL;DR: The literature on the incidence, prevalence and mortality rates of eating disorders is discussed, with anorexia nervosa the most striking and binge eating disorder is more common among males and older individuals.
Journal ArticleDOI
Checking the Cox model with cumulative sums of martingale-based residuals
TL;DR: In this article, a new class of graphical and numerical methods for checking the adequacy of the Cox regression model is presented, derived from cumulative sums of martingale-based residuals over follow-up time and covariate values.
Mortality Rates in Patients With Anorexia Nervosa and Other Eating Disorders
TL;DR: The study found age at assessment to be a significant predictor of mortality for patients with anorexia nervosa, and further research is needed to identify predictors of mortality in patients with BN and EDNOS.