Journal ArticleDOI
α‐Oxoketenes ‐ Preparation and Chemistry
Reads0
Chats0
TLDR
The most important classes of precursor molecules are 2-diazo-1, 3-diketones, 1,3dioxin-4-ones, 2,3-dihydrofuran-2, 3diones, and beta-ketoacid derivatives.Abstract:
This review describes the methods of generation of alpha-oxoketenes and their use in synthesis. While the ketenes are often generated in situ without direct proof for their existence, methods used for their direct observation are also emphasized. The most important classes of precursor molecules are 2-diazo-1,3-diketones, 1,3-dioxin-4-ones, 2,3-dihydrofuran-2,3-diones, and beta-ketoacid derivatives. Synthetically useful reactions are nucleophilic additions to give carboxylic acid derivatives which can be subjected to further functional group manipulation, [2 + 2] cycloadditions to give four-membered rings, and [2 + 4] cycloaddition chemistry with a wide variety of double-and triple-bonded dienophiles, resulting in numerous six-membered heterocyclic ring systems.read more
Citations
More filters
Journal ArticleDOI
Reactivity of dehydroacetic acid in organic synthesis
Ahmed A. Fadda,Khaled M. Elattar +1 more
TL;DR: A review of the reactivity of dehydroacetic acid can be found in this article, where the structure of the title compound was investigated and the reaction mechanisms of the reaction were discussed.
Journal ArticleDOI
Synthesis, structural and spectral studies of N-p-methylbenzyliden-N-phenyl-p,p′-dimethoxybenzoyl acetic acid hydrazide
TL;DR: The structure of the organic derivative of N-p-methylbenzyliden-N-phenyl-p,p'-dimethoxybenzoyl acetic acid hydrazide, [C 32 H 28 N 2 O 5 ], has been determined by X-ray diffraction.
References
More filters
Journal ArticleDOI
α-Oxoketenes - Preparation and Chemistry
TL;DR: The most important classes of precursor molecules are 2-diazo-1, 3-diketones, 1,3dioxin-4-ones, 2,3-dihydrofuran-2, 3diones, and beta-ketoacid derivatives as mentioned in this paper.