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Journal ArticleDOI

Activated Nitriles in Heterocyclic Synthesis: The Reaction of Cinnamonitrile Derivatives with Active Methylene Reagents

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TLDR
In this paper, the reaction of substituted cinnamonitrile derivatives with cyanoacetanilide and ethyl acetoacetate is reported, and several new polyfunctional pyridine and pyran derivatives could be synthesised.
Abstract
The reaction of substituted cinnamonitrile derivatives with cyanoacetanilide and ethyl acetoacetate is reported. Several new polyfunctional pyridine and pyran derivatives could be synthesised. The structures of the prepared compounds and the mechanisms of their formation is reported.

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Journal ArticleDOI

Cyanoacetamides and their thio- and selenocarbonyl analogues as promising reagents for fine organic synthesis

TL;DR: In this paper, the use of cyanoacetamides, cyanothio-and -======selenoacetamide in fine organic synthesis and the prospects of application of these compounds in combinatorial synthesis are analysed and generalised.
Journal ArticleDOI

Nitriles in Heterocyclic Synthesis: Synthesis of New Pyrazolo [1,5-a]pyrimidines, Pyrano[2,3-c]pyrazoles and Pyrano[3,4-c] pyrazoles

TL;DR: New pyrazolo[1,5-a]pyrimidines, pyrano[2,3-c]pyrazoles and Pyrano[3,4-c]-pyrazole were synthesised by reaction of the α,β-unsaturated nitriles 1, 13 and 16 with 3-amino-2-pyrazolin-5-one (2), 1-phenylpyrazolidine-3, 5-dione (5), and 5-aminimally-polyphenyl pyrazole (10)
Journal ArticleDOI

Activated nitriles in heterocyclic synthesis. The reaction of cinnamonitrile derivatives with active methylene reagents

TL;DR: The reaction of substituted cinnamonitrile derivatives with cyanoacetanilide and with ethyl acetoacetate produced several new polyfunctional pyridine and pyran derivatives.
Journal ArticleDOI

α, β-Unsaturated Nitriles in Heterocyclic Synthesis: Synthesis of Several Arylpyridine and Arylpyridazine Derivatives

TL;DR: Several new azabiaryls and diazabiaryl were synthesized utilizing readily obtainable α, β-unsaturated nitriles as discussed by the authors, and β-Ungesattigte Nitrile fur die Heterocyclen-Synthese: Synthese einiger arlpyridine and Arylpyridazine.