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Journal ArticleDOI

Adaptive control of dissolved oxygen concentration in a bioreactor

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TLDR
Experimental results showed that the new adaptive DO concentration control algorithm performed better than other algorithms tested, a PID controller and adaptive algorithms without the DO electrode dynamics.
Abstract
A new adaptive DO (dissolved oxygen) concentration control algorithm considering DO electrode dynamics with response time delay has been developed. A system model with two time-varying parameters was used to relate the DO concentration with two control variables: air flow rate and agitation speed. Parameters of this model were estimated on-line using a regularized constant trace recursive least-squares method. An extended Kalman filter was used to remove the effect of noises from the DO concentration measurements and thus to improve control performance. A discrete one-step ahead control scheme was adopted to determine control actions based on the parameter estimation results. Experimental results showed that the new adaptive DO concentration control algorithm performed better than other algorithms tested, a PID controller and adaptive algorithms without the DO electrode dynamics.

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Citations
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Journal ArticleDOI

Nonlinear control strategies for continuous fermenters

TL;DR: In this paper, the dilution rate and feed substrate concentration are considered as manipulated inputs in single-input/single-output strategies for productivity control in continuous fermenters and compared theoretically and via simulation.
Journal ArticleDOI

Set-point regulation of an anaerobic digestion process with bounded output feedback

TL;DR: This work addresses the robust output feedback tracking problem for a biological wastewater treatment process in the presence of input constraints and limited knowledge on the process parameters by designing a bounded output feedback control law.
Book ChapterDOI

Control of Batch Reactors: A Review

TL;DR: This paper reviews the progress in the field of batch reactor control and particular developments in model based control that have been applied to batch reactors, theoretical and experimental experience reported in literature are addressed.
Dissertation

Probing Control of Glucose Feeding in Escherichia coli Cultivations

Mats Åkesson
TL;DR: A glucose feeding strategy for E. coli cultivations that avoids acetate formation in spite of process variations and without prior knowledge of the particular strain and product is presented.
Journal ArticleDOI

Advanced control of dissolved oxygen concentration in fed batch cultures during recombinant protein production

TL;DR: It is finally shown that the new pO2 controller leads to significant improvements in the signal-to-noise ratio of other key process variables and, thus, to a higher process quality.
References
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Journal ArticleDOI

On self tuning regulators

TL;DR: In this paper, the problem of controlling a system with constant but unknown parameters is considered and an algorithm obtained by combining a least squares estimator with a minimum variance regulator computed from the estimated model is analyzed.
Journal ArticleDOI

Robustness of continuous-time adaptive control algorithms in the presence of unmodeled dynamics

TL;DR: It is concluded that existing adaptive control algorithms, as presented in the literature referenced in this paper, cannot be used with confidence in practical designs where the plant contains unmodeled dynamics because instability is likely to result.
Journal ArticleDOI

Paper: Practical issues in the implementation of self-tuning control

TL;DR: In this paper, the authors discuss the implementation aspects of self-tuning regulators and how to implement them in a real-world environment, including robustness, signal conditioning, parameter tracking, estimator wind-up, reset action and start-up.
Journal Article

Practical issues in the implementation of self-tuning control

TL;DR: Some aspects of how to implement self-tuning controllers are discussed, including robustness, signal conditioning, parameter tracking, estimator wind-up, reset action and start-up.
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