Analysis of 3-Dimensional Arch Anatomy, Vascular Flow, and Postnatal Outcome in Cases of Suspected Coarctation of the Aorta Using Fetal Cardiac Magnetic Resonance Imaging
David F. A. Lloyd,David F. A. Lloyd,Milou P. M. van Poppel,Kuberan Pushparajah,Kuberan Pushparajah,Trisha V. Vigneswaran,Vita Zidere,Johannes K. Steinweg,Joshua F.P. van Amerom,Thomas A. Roberts,Alexander Schulz,Marietta Charakida,Owen Miller,Gurleen Sharland,Mary A. Rutherford,Joseph V. Hajnal,John M. Simpson,Reza Razavi,Reza Razavi +18 more
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TLDR
In this article, the authors identify fetuses at risk of severe neonatal coarctation of the aorta (CoA) in clinical practice with a high rate of false positives.Abstract:
Background: Identifying fetuses at risk of severe neonatal coarctation of the aorta (CoA) can be lifesaving but is notoriously challenging in clinical practice with a high rate of false positives. ...read more
Citations
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Journal ArticleDOI
Cerebral Blood Flow Monitoring in High-Risk Fetal and Neonatal Populations
Rachel L. Leon,Eric B. Ortigoza,Noorjahan Ali,Dimitrios G. Aggelis,Joshua S. Wolovits,Lina F. Chalak +5 more
TL;DR: CBF monitoring in fetuses with intrauterine growth restriction, anemia, congenital heart disease, neonates born preterm and those with hypoxic-ischemic encephalopathy are discussed.
Posted ContentDOI
Automated 3D reconstruction of the fetal thorax in the standard atlas space from motion-corrupted MRI stacks for 21-36 weeks GA range
Alena Uus,Irina Grigorescu,Milou P. M. van Poppel,Johannes K. Steinweg,Thomas A. Roberts,Mary A. Rutherford,Joseph V. Hajnal,David F. A. Lloyd,Kuberan Pushparajah,Maria Deprez +9 more
TL;DR: In this paper, a 3D CNN-based intrauterine localisation of the fetal trunk and landmark-guided pose estimation steps are used to reconstruct the fetal thorax region for 21-36 weeks GA range MRI datasets.
Journal ArticleDOI
Automated 3D reconstruction of the fetal thorax in the standard atlas space from motion-corrupted MRI stacks for 21–36 weeks GA range
TL;DR: In this paper , a fully automated pipeline for reconstruction of the fetal thorax region for 21-36 weeks GA range T2-weighted MRI datasets is proposed, which includes 3D CNN-based intra-uterine localisation and landmark-guided pose estimation steps.
Journal ArticleDOI
3D Approaches in Complex CHD: Where Are We? Funny Printing and Beautiful Images, or a Useful Tool?
A. Spanaki,Saleha Kabir,Natasha Stephenson,Milou P. M. van Poppel,Valentina Benetti,J. Simpson +5 more
TL;DR: Overall, the use of 3D imaging has resulted in a better understanding of anatomy, with a direct impact on the surgical and catheter approach, particularly in more complex cases.
Journal ArticleDOI
Fetal cardiovascular blood flow MRI: techniques and applications.
Joshua F.P. van Amerom,Datta Singh Goolaub,Eric M. Schrauben,Liqun Sun,Mike Seed,Christopher K. Macgowan +5 more
TL;DR: Details of the techniques used in fetal cardiovascular blood flow MRI, including single slice and volumetric imaging sequences, post-processing and analysis, along with a summary of applications in human studies and animal models are provided.
References
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Journal ArticleDOI
Hemodynamic considerations in the development of narrowing of the aorta
TL;DR: It was postulated that constriction of the ductus arteriosus after birth would produce obstruction, and this was confirmed experimentally in fetal lambs with surgically simulated juxtaductal coarctation.
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Prenatal diagnosis of coarctation of the aorta improves survival and reduces morbidity
TL;DR: Whether antenatal diagnosis of coarctation of the aorta results in reduced mortality and improved preoperative haemodynamic stability compared with postnatal diagnosis is investigated to investigate.
Journal ArticleDOI
Aortic dilation in bicuspid aortic valve disease: Flow pattern is a major contributor and differs with valve fusion type
Malenka M. Bissell,Aaron T. Hess,Luca Biasiolli,Steffan J. Glaze,Margaret Loudon,Alex Pitcher,Anne Davis,Bernard D. Prendergast,Michael Markl,Alex J. Barker,Stefan Neubauer,Saul G. Myerson +11 more
TL;DR: In this paper, the authors used cardiovascular MR to understand the pathophysiology better by examining the links between 3-dimensional flow abnormalities, aortic function, and aortric dilation.
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Coarctation, tubular hypoplasia, and the ductus arteriosus. Histological study of 35 specimens.
Siew Yen Ho,Robert H. Anderson +1 more
TL;DR: The histological study showed that the ductus was easily distinguished from the walls of the aorta or pulmonary artery, and the anatomical study of the hearts with obstructive aortic lesions emphasised the necessity of distinguishing 'coarctation' from 'tubular hypoplasia'.
Journal ArticleDOI
Impaired Elastic Properties of the Ascending Aorta in Newborns Before and Early After Successful Coarctation Repair Proof of a Systemic Vascular Disease of the Prestenotic Arteries
Manfred Vogt,Andreas Kühn,Daniela Baumgartner,Christian Baumgartner,Raymonde Busch,Martin Kostolny,John Hess +6 more
TL;DR: Elastic properties of the prestenotic aorta of patients with coarctation seem to be impaired primarily, even in neonates, and remain unchanged early after successful operation, suggesting that surgical correction does not resolve inborn pathology of the aortic vascular bed.