Open AccessJournal Article
Anti-diarrhoeal potential of Asparagus racemosus wild root extracts in laboratory animals.
Venkatesan N,Thiyagarajan,S. Narayanan,Arul A,S. Raja,Vijaya Kumar Sg,Rajarajan T,J.B. Perianayagam +7 more
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TLDR
The results point out the possible anti-diarrhoeal effect of the plant extracts and substantiate the use of this herbal remedy as a non-specific treatment for diarrhoea in folk medicine.Abstract:
PURPOSE: Asparagus racemosus Wild root has been used traditionally in Ayurveda for the treat- ment of diarrhoea and dysentery. However, the claims of Ayurveda need to be validated by a suitable experi- mental model. Therefore, the present study was under- taken to evaluate the effect of ethanol and aqueous extracts of Asparagus racemosus for its antidiarrhoeal potential against several experimental models of diar- rhoea in Albino Wistar rats. METHODS: The antidi- arrhoeal activity of ethanol and aqueous extracts of Asparagus racemosus root was evaluated using castor oil-induced diarrhoea model in rats. Further, we evalu- ated the effect of ethanol and aqueous extracts on gas- trointestinal tract motility after charcoal meal administration and PGE 2 induced intestinal fluid accu- mulation (enteropooling). Loperamide was used as pos- itive control. RESULTS: The plant extracts showed significant (P < 0.05) inhibitor activity against castor oil induced diarrhoea and PGE 2 induced enteropooling in rats when tested at 200 mg/kg. Both extracts also showed significant (P < 0.001) reduction in gas- trointestinal motility in charcoal meal test in rats. CONCLUSION: The results point out the possible anti-diarrhoeal effect of the plant extracts and substan- tiate the use of this herbal remedy as a non-specific treatment for diarrhoea in folk medicine.read more
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Asparagus racemosus--ethnopharmacological evaluation and conservation needs.
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Studies on the antidiarrhoeal activity of Aegle marmelos unripe fruit: Validating its traditional usage
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Antidiarrhoeal and antimicrobial activity of Calpurnia aurea leaf extract
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References
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Book
Park's Textbook Of Preventive And Social Medicine
TL;DR: Park's textbook of preventive and social medicine as mentioned in this paper, Park's book of preventive, social, and preventive medicine, and Park's text of social medicine, is a good starting point for our work.
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The magnitude of the global problem of acute diarrhoeal disease: a review of active surveillance data.
J. D. Snyder,Michael H. Merson +1 more
TL;DR: Morbidity rates were found to be highest in the 6-11 month age group, while the mortality rates were greatest in infants under 1 year of age and children 1 year old.
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Study of antidiarrhoeal activity of four medicinal plants in castor-oil induced diarrhoea.
F.Gricilda Shoba,Molly Thomas +1 more
TL;DR: The methanolic plant extracts significantly reduced induction time of diarrhoea and total weight of the faeces and establish the efficacy of these plant extracts as antidiarrhoeal agents.