Open AccessJournal Article
Antidiabetic activity of Momordica charantia seeds on streptozotocin induced diabetic rats.
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TLDR
Both the varieties showed safe and significant hypoglycemic effects which were more pronounced in MC SEt1 compared to MCSEt2 and glibenclamide, and clearly show the antidiabetic properties of Momordica charantia.Abstract:
The present study was aimed to evaluate the hypoglycemic efficacy in an aqueous extract of seeds of two varieties, namely a country and a hybrid variety of Momordica charantia (MCSEt1 and MCSEt2) respectively in streptozotocin (STZ) induced diabetic rats STZ-induced diabetic rats were treated with aqueous extracts of MCSEt1 and t2 for a period of 30 days MCSEt1 and t2 extract treatment to diabetic rats resulted in a significant reduction in blood glucose, glycosylated hemoglobin, lactate dehydrogenase, glucose-6-phosphatase, fructose-1,6-bisphosphatase and glycogen phosphorylase, and a concomitant increase in the levels of hemoglobin, glycogen and activities of hexokinase and glycogen synthase These results clearly show the antidiabetic properties of Momordica charantia Both the varieties showed safe and significant hypoglycemic effects which were more pronounced in MCSEt1 compared to MCSEt2 and glibenclamideread more
Citations
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Leads from Indian medicinal plants with hypoglycemic potentials
TL;DR: This article aims to provide a comprehensive review on various plant species from Indian biosphere and their constituents, which have been shown to display potent hypoglycemic activity.
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Animal models to test drugs with potential antidiabetic activity.
TL;DR: The available animal models of diabetes and some in vitro models which have been used as tools to investigate the mechanism of action of drugs with potential antidiabetic properties are reviewed to contribute to the researcher in the ethnopharmacology field to designs new strategies for the development of novel drugs to treat this serious condition.
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Bitter Gourd (Momordica charantia): a Dietary Approach to Hyperglycemia
TL;DR: Bitter gourd has the potential to become a component of the diet or a dietary supplement for diabetic and prediabetic patients and well-designed interdisciplinary research by nutritionists, medical doctors, and agronomists is needed before a dietary recommendation can be given and a product brought to the market.
Journal Article
Antioxidant properties of Momordica Charantia (bitter gourd) seeds on Streptozotocin induced diabetic rats.
TL;DR: The results clearly suggest that seeds of Momordica charantia treated group may effectively normalize the impaired antioxidant status in streptozotocin induced-diabetes than the glibenclamide treated groups.
Journal Article
A pharmacological evaluation of medicinal plants used by folk medicinal practitioners of Station Purbo Para village of Jamalpur Sadar Upazila in Jamalpur district, Bangladesh.
Mohammed Rahmatullah,Rownak Jahan,Mst. Afsana Khatun,Farhana Israt Jahan,Abul Kalam Azad,A. B. M. A. Bashar,Z. U. M. E. U. Miajee,Shamima Ahsan,Nusratun Nahar,Ishtiaq Ahmad,Majeedul H. Chowdhury +10 more
TL;DR: The present study demonstrates that a substantial percentage of plants should be scientifically studied as soon as possible in a thorough manner for they can be sources of potentially important and efficacious drugs.
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