Journal ArticleDOI
Assessment of platelet transfusion for reversal of aspirin after traumatic brain injury.
Arshad M. Bachelani,Joshua T. Bautz,Jason L. Sperry,Alain Corcos,Mazen S. Zenati,Timothy R. Billiar,Andrew B. Peitzman,Gary T. Marshall +7 more
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TLDR
The Aspirin Response Test should be used to better target and guide platelet transfusions in TBI patients with known or suspected ASA use history and the adequate volume of platelets administered to correct drug-induced dysfunction.About:
This article is published in Surgery.The article was published on 2011-10-01. It has received 71 citations till now. The article focuses on the topics: Platelet transfusion.read more
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The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition
Rolf Rossaint,Bertil Bouillon,Vladimir Cerny,Timothy J Coats,Jacques Duranteau,Enrique Fernández-Mondéjar,Daniela Filipescu,Beverley J. Hunt,Radko Komadina,Giuseppe Nardi,Edmund Neugebauer,Yves Ozier,Louis Riddez,Arthur Schultz,Jean Louis Vincent,Donat R. Spahn +15 more
TL;DR: The guideline now recommends that patients be transferred directly to an appropriate trauma treatment centre and encourages use of a restricted volume replacement strategy during initial resuscitation, and may also serve as a basis for local implementation.
Journal ArticleDOI
Management of bleeding and coagulopathy following major trauma: an updated European guideline
Donat R. Spahn,Bertil Bouillon,Vladimir Cerny,Timothy J Coats,Jacques Duranteau,Enrique Fernández-Mondéjar,Daniela Filipescu,Beverley J. Hunt,Radko Komadina,Giuseppe Nardi,Edmund Neugebauer,Yves Ozier,Louis Riddez,Arthur Schultz,Jean Louis Vincent,Rolf Rossaint +15 more
TL;DR: Key changes encompassed in this version of the guideline include new recommendations on the appropriate use of vasopressors and inotropic agents, and reflect an awareness of the growing number of patients in the population at large treated with antiplatelet agents and/or oral anticoagulants.
This Provisional PDF corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. Management of bleeding and coagulopathy following major trauma: an updated European guideline
Donat R. Spahn,Bertil Bouillon,Timothy J Coats,Jacques Duranteau,Enrique Fernández-Mondéjar,Daniela Filipescu,Beverley J. Hunt,Giuseppe Nardi,Edmund Neugebauer,Louis Riddez,Arthur Schultz,Jean Louis Vincent +11 more
TL;DR: In this article, the authors presented an updated version of the guideline published by the Task Force for Advanced Bleeding Care in Trauma and updated in 2010, which included new recommendations on the appropriate use of vasopressors and inotropic agents.
Journal ArticleDOI
Coagulopathy and haemorrhagic progression in traumatic brain injury: advances in mechanisms, diagnosis, and management
Marc Maegele,Herbert Schöchl,Tomas Menovsky,Hugues Maréchal,Niklas Marklund,Andras Buki,Simon J. Stanworth +6 more
TL;DR: The main challenge for management is to address therisk of hypocoagulopathy with prolonged bleeding and progression of haemorrhagic lesions, and the risk of hypercoagulopathic with an increased prothrombotic tendency also warrants consideration.
Journal ArticleDOI
Coagulopathy after traumatic brain injury: incidence, pathogenesis, and treatment options
TL;DR: Hemocoagulative disorders after TBI may be amenable to treatment, and adequate and timely management may protect from secondary injury and poor outcomes.
References
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Journal ArticleDOI
Incidence of traumatic brain injury in the United States, 2003.
TL;DR: Findings were similar to those from previous years in which rates of TBI were highest for young children (aged 0–4) and men, and the leading causes were falls and motor vehicle traffic.
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The incidence of fall injury events among the elderly in a defined population
Richard W. Sattin,Deborah A. Lambert Huber,Carolee A. DeVito,Juan G. Rodriguez,Alberto Ros,Sandro Bacchelli,Judy A. Stevens,Richard J. Waxweiler +7 more
TL;DR: The rate of fall injury events coming to acute medical attention increased exponentially with age for both elderly men and women (predominantly white), reaching a high for those aged 85 years or more of 138.5 per 1,000 for males and 158.8 for females.
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An aging world : 2001
TL;DR: In this article, the 7th major cross-national report in a US Census Bureau series on the worlds elderly/older populations focuses primarily on people aged 65 years old and over.
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The Role of Aspirin in Cardiovascular Prevention: Implications of Aspirin Resistance
TL;DR: The clinical implications of aspirin resistance are explored in various cardiovascular disease states, including diabetes mellitus, hypertension, heart failure, and other similar disorders where platelet reactivity is enhanced.
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Intracranial Complications of Preinjury Anticoagulation in Trauma Patients with Head Injury
Alfred A. Mina,John F Knipfer,David Y. Park,Holly A. Bair,Greg A. Howells,Phillip J. Bendick +5 more
TL;DR: These data indicate that the trauma patient with preinjury anticoagulation such as warfarin or even aspirin who has an intracranial injury has a four- to fivefold higher risk of death than the nonanticoagulated patient.